ID   NP_ADEG1                Reviewed;          72 AA.
AC   Q89707;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   29-SEP-2021, entry version 74.
DE   RecName: Full=Pre-histone-like nucleoprotein;
DE   AltName: Full=Pre-core protein VII;
DE            Short=pVII;
DE   Contains:
DE     RecName: Full=Histone-like nucleoprotein;
DE              Short=NP;
DE     AltName: Full=Core protein VII;
OS   Fowl adenovirus A serotype 1 (strain CELO / Phelps) (FAdV-1) (Avian
OS   adenovirus gal1 (strain Phelps)).
OC   Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC   Rowavirales; Adenoviridae; Aviadenovirus; Fowl aviadenovirus A.
OX   NCBI_TaxID=10553;
OH   NCBI_TaxID=8976; Galliformes.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8634026; DOI=10.1007/bf01718405;
RA   Akopian T.A., Lazareva S.E., Tikhomirov E.E., Karpov V.A., Naroditsky B.S.;
RT   "Genes for fowl adenovirus CELO penton base and core polypeptides.";
RL   Arch. Virol. 141:357-365(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=8627769; DOI=10.1128/jvi.70.5.2939-2949.1996;
RA   Chiocca S., Kurzbauer R., Schaffner G., Baker A., Mautner V., Cotten M.;
RT   "The complete DNA sequence and genomic organization of the avian adenovirus
RT   CELO.";
RL   J. Virol. 70:2939-2949(1996).
CC   -!- FUNCTION: Strongly bound to viral DNA and responsible for wrapping and
CC       condensing the viral DNA. Probably promotes viral genome import into
CC       the nucleus and is still associated with the viral DNA when the latter
CC       enters into the host nucleus (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with the core-capsid bridging protein; this
CC       interaction bridges the virus core to the capsid. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: [Pre-histone-like nucleoprotein]: Host nucleus,
CC       host nucleolus {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: [Histone-like nucleoprotein]: Virion
CC       {ECO:0000250}. Note=Located inside the capsid in association with the
CC       viral DNA (core). Present in about 1070 copies per virion (By
CC       similarity). {ECO:0000250}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC   -!- PTM: Cleaved near the N-terminus by the viral protease during virion
CC       maturation to form the mature protein. {ECO:0000250}.
CC   -!- MISCELLANEOUS: All late proteins expressed from the major late promoter
CC       are produced by alternative splicing and alternative polyadenylation of
CC       the same gene giving rise to non-overlapping ORFs. A leader sequence is
CC       present in the N-terminus of all these mRNAs and is recognized by the
CC       viral shutoff protein to provide expression although conventional
CC       translation via ribosome scanning from the cap has been shut off in the
CC       host cell (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the adenoviridae histone-like nucleoprotein
CC       family. {ECO:0000305}.
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DR   EMBL; Z48167; CAA88182.1; -; Genomic_DNA.
DR   EMBL; U46933; AAC54909.1; -; Genomic_DNA.
DR   PIR; S52322; S52322.
DR   RefSeq; NP_043883.1; NC_001720.1.
DR   GeneID; 1476561; -.
DR   Proteomes; UP000001594; Genome.
DR   GO; GO:0044196; C:host cell nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0075732; P:viral penetration into host nucleus; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Acetylation; DNA-binding; Host nucleus; Late protein; Reference proteome;
KW   Viral penetration into host nucleus; Virion; Virus entry into host cell.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..72
FT                   /note="Pre-histone-like nucleoprotein"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000421441"
FT   PROPEP          2..14
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000036593"
FT   CHAIN           15..72
FT                   /note="Histone-like nucleoprotein"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000036594"
FT   SITE            14..15
FT                   /note="Cleavage; by adenovirus protease"
FT   MOD_RES         2
FT                   /note="N-acetylserine; by host"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   72 AA;  8563 MW;  1BE1D163BAA6A1EF CRC64;
     MSILISPSDN RGWGANMRYR RRASMRGVGR RRLTLRQLLG LGSRRRRRSR PTTVSNRLVV
     VSTRRRSSRR RR