ID   AROF_CATRO              Reviewed;         493 AA.
AC   A0MH68;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 2.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Probable phospho-2-dehydro-3-deoxyheptonate aldolase, chloroplastic;
DE            EC=2.5.1.54;
DE   AltName: Full=3-deoxy-D-arabino-heptulosonate 7-phosphate synthase;
DE   AltName: Full=CrDHS1;
DE   AltName: Full=DAHP synthase;
DE   AltName: Full=Phospho-2-keto-3-deoxyheptonate aldolase;
DE   Flags: Precursor;
GN   Name=DHS1;
OS   Catharanthus roseus (Madagascar periwinkle) (Vinca rosea).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae;
OC   Catharanthinae; Catharanthus.
OX   NCBI_TaxID=4058;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Ramani S., Chelliah J.;
RL   Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702; EC=2.5.1.54;
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis;
CC       chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step
CC       1/7.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the class-II DAHP synthase family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABK29527.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; DQ859024; ABK29527.1; ALT_FRAME; mRNA.
DR   AlphaFoldDB; A0MH68; -.
DR   SMR; A0MH68; -.
DR   UniPathway; UPA00053; UER00084.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002480; DAHP_synth_2.
DR   PANTHER; PTHR21337; PTHR21337; 1.
DR   Pfam; PF01474; DAHP_synth_2; 2.
PE   2: Evidence at transcript level;
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Chloroplast;
KW   Plastid; Transferase; Transit peptide.
FT   TRANSIT         1..58
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           59..493
FT                   /note="Probable phospho-2-dehydro-3-deoxyheptonate
FT                   aldolase, chloroplastic"
FT                   /id="PRO_0000312804"
SQ   SEQUENCE   493 AA;  54743 MW;  EF247BADC19098AB CRC64;
     MAMSNTSALA SKLLPSCKPH QPTLTFFSPS TTCQKKPRSS RPISAAVHVT QPPKTPISSA
     TATKRRLSLL NGVWESWKSK KALQLPEYPD EGKLDGVLKT IEAFPPLVFA GEARSLEEKL
     AQAAMGNAFL LQGGDCAESF KELMPLYSRY FQNTASDECR LTFGGQCPVI KVGRMAGQFA
     KPRLDPFEEK DGLWLSGANG WPVAWEAYCK LQQLSPSRAL LLVVCCYAES HPMDLDFVEH
     SEQGDRYQEL AHRVDEALGF MDACGLTVDH PIMATTEFWT SHECLLLPYE QALTREDSTS
     GLFYDCSAHM LWVGERTRQL DGAHVEFLRG VANPLGIKVS QKMDPNELVN LIEILNPTNK
     PGRITVIVRM GAENMRVKLP HLIRAVRGAG QIVTWVCDPM HGNTIKAPCG LKTRAFDAIL
     AEVRAFYDVH EQEGTLPGTE CVGGSRTITY DDRQTRYHTH CDPRLNASQS LELAFIIAER
     LRKEESVLNA HSP