ID   AROF_ORYSJ              Reviewed;         554 AA.
AC   Q75LR2; Q75W15;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 2.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase 1, chloroplastic;
DE            EC=2.5.1.54;
DE   AltName: Full=3-deoxy-D-arabino-heptulosonate 7-phosphate synthase 1;
DE   AltName: Full=DAHP synthase 1;
DE   AltName: Full=Phospho-2-keto-3-deoxyheptonate aldolase 1;
DE   Flags: Precursor;
GN   Name=DAHPS1; OrderedLocusNames=Os03g0389700, LOC_Os03g27230;
GN   ORFNames=OSJNBa0017N12.13;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Fujiminori;
RA   Mase K., Nishikubo N., Satou K., Nakano Y., Kajita S., Katayama Y.;
RT   "The cDNA encoding 3-deoxy-D-arabino heptulosonate-7-phosphate synthase
RT   expressed in rice stem.";
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Fujiminori;
RA   Mase K., Nishikubo N., Satou K., Nakano Y., Kajita S., Katayama Y.;
RT   "The gene encoding 3-deoxy-D-arabino heptulosonate-7-phosphate synthase
RT   expressed in rice stem.";
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16109971; DOI=10.1101/gr.3869505;
RG   The rice chromosome 3 sequencing consortium;
RA   Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA   Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA   Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA   Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA   Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA   Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA   Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA   Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA   Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA   Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA   O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA   Jin W., Lee H.R., Jiang J., Jackson S.;
RT   "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT   and diverged grass species.";
RL   Genome Res. 15:1284-1291(2005).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [5]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702; EC=2.5.1.54;
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis;
CC       chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step
CC       1/7.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the class-II DAHP synthase family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAR06362.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAD14924.1; Type=Frameshift; Evidence={ECO:0000305};
CC       Sequence=BAD14927.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; AB122057; BAD14924.1; ALT_FRAME; mRNA.
DR   EMBL; AB122083; BAD14927.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; AC092075; AAR06362.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014959; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_015630375.1; XM_015774889.1.
DR   AlphaFoldDB; Q75LR2; -.
DR   SMR; Q75LR2; -.
DR   STRING; 4530.OS03T0389700-01; -.
DR   PaxDb; Q75LR2; -.
DR   PRIDE; Q75LR2; -.
DR   GeneID; 4333014; -.
DR   KEGG; osa:4333014; -.
DR   eggNOG; ENOG502QPP7; Eukaryota.
DR   HOGENOM; CLU_026885_3_0_1; -.
DR   InParanoid; Q75LR2; -.
DR   OrthoDB; 546472at2759; -.
DR   PlantReactome; R-OSA-1119430; Chorismate biosynthesis.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000000763; Chromosome 3.
DR   Proteomes; UP000059680; Chromosome 3.
DR   Genevisible; Q75LR2; OS.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 2.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002480; DAHP_synth_2.
DR   PANTHER; PTHR21337; PTHR21337; 1.
DR   Pfam; PF01474; DAHP_synth_2; 1.
DR   TIGRFAMs; TIGR01358; DAHP_synth_II; 1.
PE   2: Evidence at transcript level;
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Chloroplast;
KW   Plastid; Reference proteome; Transferase; Transit peptide.
FT   TRANSIT         1..39
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           40..554
FT                   /note="Phospho-2-dehydro-3-deoxyheptonate aldolase 1,
FT                   chloroplastic"
FT                   /id="PRO_0000247310"
FT   REGION          41..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   554 AA;  60490 MW;  CC3DB62F55DC79AC CRC64;
     MSLATSSSMA GGAAVVPRSA TATTASAFVT MKRRATAVRA VHAAEPSKNP PVGVPSAAKT
     SSPSVAAPEK APVAAAPAPV APAPAATKQV APARWAVDSW RTKKALQLPE YPNAAELEAV
     LKTIEAFPPI VFAGEARHLE ERLADAAMGR AFLLQGGDCA ESFKEFNGNN IRDTFRVLLQ
     MSAVLTFGGQ MPVIKVGRMA GQFAKPRSEA FEERDGVKLP SYRGDNINGD AFNEKSRIPD
     PQRMVRAYAQ SAATLNLLRA FATGGYAAMQ RVTQWNLDFT QHSEQGDRYR ELAHRVDEAL
     GFMSAAGLTV DHPLMTSTDF WTSHECLLLP YEQSLTRQDS TTGHFYDCSA HMLWVGERTR
     QLDGAHVEFL RGVANPLGIK VSDKMNPTEL VKLIEILNPS NKPGRITIIT RMGAENMRVK
     LPHLIRAVRH AGQIVTWITD PMHGNTIKAP CGLKTRPFDS IAEVRAFFDV HDQEGSHPGG
     VHLEMTGQNV TECIGGSRTV TFDDLGDRYH THCDPRLNAS QSLELSFIIA ERLRRKRIRS
     SKLNNMLPLP PFGV