ID   AROF_SOLLC              Reviewed;         511 AA.
AC   P37215;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 114.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase 1, chloroplastic;
DE            EC=2.5.1.54;
DE   AltName: Full=3-deoxy-D-arabino-heptulosonate 7-phosphate synthase 1;
DE   AltName: Full=DAHP synthase 1;
DE   AltName: Full=Phospho-2-keto-3-deoxyheptonate aldolase 1;
DE   Flags: Precursor;
OS   Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC   Solanum subgen. Lycopersicon.
OX   NCBI_TaxID=4081;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. UC82B;
RX   PubMed=7902741; DOI=10.1007/bf00021525;
RA   Goerlach J., Beck A., Henstrand J.M., Handa A.K., Herrmann K.M., Schmid J.,
RA   Amrhein N.;
RT   "Differential expression of tomato (Lycopersicon esculentum L.) genes
RT   encoding shikimate pathway isoenzymes. I. 3-deoxy-D-arabino-heptulosonate
RT   7-phosphate synthase.";
RL   Plant Mol. Biol. 23:697-706(1993).
CC   -!- FUNCTION: May be involved in the synthesis of secondary metabolites
CC       derived from intermediates of the pre-chorismate pathway up to
CC       shikimate.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702; EC=2.5.1.54;
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis;
CC       chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step
CC       1/7.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast.
CC   -!- TISSUE SPECIFICITY: Higher levels seen in the cotyledons than in the
CC       leaves and flowers. Lower levels seen in the roots and stems.
CC   -!- SIMILARITY: Belongs to the class-II DAHP synthase family.
CC       {ECO:0000305}.
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DR   EMBL; Z21792; CAA79855.1; -; mRNA.
DR   PIR; S40411; S40411.
DR   AlphaFoldDB; P37215; -.
DR   SMR; P37215; -.
DR   STRING; 4081.Solyc11g009080.1.1; -.
DR   PaxDb; P37215; -.
DR   eggNOG; ENOG502QPP7; Eukaryota.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000004994; Unplaced.
DR   ExpressionAtlas; P37215; baseline and differential.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0009611; P:response to wounding; IEA:EnsemblPlants.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002480; DAHP_synth_2.
DR   PANTHER; PTHR21337; PTHR21337; 1.
DR   Pfam; PF01474; DAHP_synth_2; 1.
DR   TIGRFAMs; TIGR01358; DAHP_synth_II; 1.
PE   2: Evidence at transcript level;
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Chloroplast;
KW   Plastid; Reference proteome; Transferase; Transit peptide.
FT   TRANSIT         1..49
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           50..511
FT                   /note="Phospho-2-dehydro-3-deoxyheptonate aldolase 1,
FT                   chloroplastic"
FT                   /id="PRO_0000002300"
SQ   SEQUENCE   511 AA;  57120 MW;  E7725992C42BEA4C CRC64;
     MALSNTLSLS SSKSLVQSHL LHNPTPQPRF SLFPTTQHGR RHPISAVHAA EPSKTAVKQG
     KWSLDSWKTK KALQLPEYPD EKELESVLKT LEMNPPLVFA GEARSLEEKL GEAALGKAFL
     LQGGDCAESF KEFNANNIRD TFRILLQMSV VLMFGGQVPV IKVGRMAGQF AKPRSDPFEE
     INGVKLPSYK GDNINGDTFD EKSRIPDPHR LIRAYMQSAA TLNLLRAFAT GGYAAMQRVT
     EWNLDFVENS EQGDRYQELA HRVDEALGFM AAAGLTVDHP IMSTTDFWTS HECLLLPYEQ
     ALTREDSTSG LFYDCSAHMV WVGERTRQLD GAHVEFLRGV ANPLGIKVSQ KMDPKELIKL
     IDILNPANKP GRITVIVRMG AENMRVKLSH LVRAVRGAGQ IVTWVCDPMH GNTIKAPCGL
     KTRAFDSIQA EVRAFFDVHE QEGSHPWCIH LEMTGQNVTE CIGGSRTVTY DDLGSRYHTH
     CDPRLNASQS LELSFIVAER LRRRRMSSQR L