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AROG_ORYSJ
ID   AROG_ORYSJ              Reviewed;         539 AA.
AC   Q75W16; Q8LH96;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase 2, chloroplastic;
DE            EC=2.5.1.54;
DE   AltName: Full=3-deoxy-D-arabino-heptulosonate 7-phosphate synthase 2;
DE   AltName: Full=DAHP synthase 2;
DE   AltName: Full=Phospho-2-keto-3-deoxyheptonate aldolase 2;
DE   Flags: Precursor;
GN   Name=DAHPS2; OrderedLocusNames=Os07g0622200, LOC_Os07g42960;
GN   ORFNames=P0594D10.136;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Fujiminori;
RA   Mase K., Nishikubo N., Satou K., Nakano Y., Kajita S., Katayama Y.;
RT   "The cDNA encoding 3-deoxy-D-arabino heptulosonate-7-phosphate synthase
RT   expressed in rice stem.";
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Fujiminori;
RA   Mase K., Nishikubo N., Satou K., Nakano Y., Kajita S., Katayama Y.;
RT   "The gene encoding 3-deoxy-D-arabino heptulosonate-7-phosphate synthase
RT   expressed in rice stem.";
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702; EC=2.5.1.54;
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis;
CC       chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step
CC       1/7.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the class-II DAHP synthase family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC10194.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AB122058; BAD15283.1; -; mRNA.
DR   EMBL; AB122082; BAD14926.1; -; Genomic_DNA.
DR   EMBL; AP004380; BAC10194.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014963; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_015646378.1; XM_015790892.1.
DR   AlphaFoldDB; Q75W16; -.
DR   SMR; Q75W16; -.
DR   BioGRID; 812983; 1.
DR   STRING; 4530.OS07T0622200-01; -.
DR   PaxDb; Q75W16; -.
DR   PRIDE; Q75W16; -.
DR   GeneID; 4343946; -.
DR   KEGG; osa:4343946; -.
DR   eggNOG; ENOG502QPP7; Eukaryota.
DR   InParanoid; Q75W16; -.
DR   OrthoDB; 546472at2759; -.
DR   PlantReactome; R-OSA-1119430; Chorismate biosynthesis.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000000763; Chromosome 7.
DR   Proteomes; UP000059680; Chromosome 7.
DR   Genevisible; Q75W16; OS.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002480; DAHP_synth_2.
DR   PANTHER; PTHR21337; PTHR21337; 1.
DR   Pfam; PF01474; DAHP_synth_2; 1.
DR   TIGRFAMs; TIGR01358; DAHP_synth_II; 1.
PE   2: Evidence at transcript level;
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Chloroplast;
KW   Plastid; Reference proteome; Transferase; Transit peptide.
FT   TRANSIT         1..54
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           55..539
FT                   /note="Phospho-2-dehydro-3-deoxyheptonate aldolase 2,
FT                   chloroplastic"
FT                   /id="PRO_0000247311"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          41..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   539 AA;  59334 MW;  69AE271D7CF17676 CRC64;
     MALATNSAAV SGGAAAAASS APQPRLAATF LPMRRRTVSA VHAADPAKSN GPVQAAAKAS
     SPSTVAAPEK KPVGLGKWTV DSWKAKKALQ LPEYPSQEEL DSVLKTIETF PPVVFAGEAR
     HLEERLADAA MGRAFVLQGG DCAESFKEFN ANNIRDTFRI LLQMGAVLMF GGQMPVVKVV
     GRMAGQFAKP RSDSFEERDG VKLPSYRGDN INGDTFDEKS RVPDPQRMIR AYAQSVATLN
     LLRAFATGGY AAMQRVTQWN LDFMDHSEQG DRRYRELAHR VDEALGFMTA AGLTVDHPIM
     TTTDFWTSHE CLLLPYEQSL TREDSTSGLF YDCSAHMLWV GERTRQLDGA HVEFLRGVAN
     PLGIKVSDKM NPRDLVKLIE ILNPSNKPGR ITIITRMGAE NMRVKLPHLI RAVRNSGQIV
     TWITDPMHGN TIKAPCGLKT RPFDSILAEV RAFFDVHDQE GSHPGGIHLE MTGQNVTECI
     GGSRTVTFDD LSDRYHTHCD PRLNASQSLE LAFIIAERLR RRRMRSGVNS NLPLPPLAF
 
 
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