ID   NR2CA_BOVIN             Reviewed;         140 AA.
AC   Q58DU8;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Nuclear receptor 2C2-associated protein;
DE   AltName: Full=TR4 orphan receptor-associated 16 kDa protein;
GN   Name=NR2C2AP; Synonyms=TRA16;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
CC   -!- FUNCTION: May act as a repressor of NR2C2-mediated transactivation by
CC       suppressing the binding between NR2C2/TR4 and the TR4-response element
CC       in target genes. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with NR2C2/TR4. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NR2C2AP family. {ECO:0000305}.
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DR   EMBL; BT021499; AAX46346.1; -; mRNA.
DR   RefSeq; NP_001029499.1; NM_001034327.1.
DR   RefSeq; XP_005208498.1; XM_005208441.2.
DR   AlphaFoldDB; Q58DU8; -.
DR   SMR; Q58DU8; -.
DR   STRING; 9913.ENSBTAP00000002311; -.
DR   PaxDb; Q58DU8; -.
DR   Ensembl; ENSBTAT00000002311; ENSBTAP00000002311; ENSBTAG00000001763.
DR   GeneID; 508684; -.
DR   KEGG; bta:508684; -.
DR   CTD; 126382; -.
DR   VEuPathDB; HostDB:ENSBTAG00000001763; -.
DR   VGNC; VGNC:32237; NR2C2AP.
DR   eggNOG; ENOG502RZAY; Eukaryota.
DR   GeneTree; ENSGT00390000017748; -.
DR   HOGENOM; CLU_133965_0_0_1; -.
DR   InParanoid; Q58DU8; -.
DR   OMA; FGRITVY; -.
DR   OrthoDB; 1412628at2759; -.
DR   TreeFam; TF300180; -.
DR   Proteomes; UP000009136; Chromosome 7.
DR   Bgee; ENSBTAG00000001763; Expressed in esophagus and 106 other tissues.
DR   ExpressionAtlas; Q58DU8; baseline.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   SUPFAM; SSF49785; SSF49785; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..140
FT                   /note="Nuclear receptor 2C2-associated protein"
FT                   /id="PRO_0000295584"
SQ   SEQUENCE   140 AA;  15929 MW;  D921BD09D8DC1EAC CRC64;
     MAHSLVCPET VSRVSSVLNR NTRQFGKKHL FDQDEETCWN SDQGPSQWVT LEFPQCICVS
     QLQIQFQGGF SSRQGRLEGS LGSEALSKIV DFYPEDNNSL QTFPVPPAEV DRLKVTFEDT
     TDFFGRVVIY HLRVLGKKKE