NR2CA_XENTR
ID NR2CA_XENTR Reviewed; 136 AA.
AC A1L1F0;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 1.
DT 03-AUG-2022, entry version 57.
DE RecName: Full=Nuclear receptor 2C2-associated protein;
DE AltName: Full=TR4 orphan receptor-associated 16 kDa protein homolog;
GN Name=nr2c2ap; Synonyms=tra16;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=N6; TISSUE=Oviduct;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May act as a repressor of nr2c2-mediated transactivation by
CC suppressing the binding between nr2c2 and its response element in
CC target genes. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NR2C2AP family. {ECO:0000305}.
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DR EMBL; BC129029; AAI29030.1; -; mRNA.
DR RefSeq; NP_001016306.1; NM_001016306.3.
DR AlphaFoldDB; A1L1F0; -.
DR SMR; A1L1F0; -.
DR STRING; 8364.ENSXETP00000056403; -.
DR DNASU; 549060; -.
DR Ensembl; ENSXETT00000100320; ENSXETP00000065246; ENSXETG00000037690.
DR GeneID; 549060; -.
DR KEGG; xtr:549060; -.
DR CTD; 126382; -.
DR Xenbase; XB-GENE-973035; nr2c2ap.
DR eggNOG; ENOG502RZAY; Eukaryota.
DR InParanoid; A1L1F0; -.
DR OrthoDB; 1412628at2759; -.
DR Proteomes; UP000008143; Chromosome 1.
DR Proteomes; UP000790000; Unplaced.
DR Bgee; ENSXETG00000037690; Expressed in egg cell and 15 other tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR012919; SUN_dom.
DR Pfam; PF07738; Sad1_UNC; 1.
DR SUPFAM; SSF49785; SSF49785; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome.
FT CHAIN 1..136
FT /note="Nuclear receptor 2C2-associated protein"
FT /id="PRO_0000295589"
SQ SEQUENCE 136 AA; 15428 MW; 9B765ED0B6BCC4CE CRC64;
MVTSVLSSVT ISRVSSVLNR DVKQFGKQFL FDGREETCWN SDQGSCQWVL MEFPQNVLVS
QIHLQFQGGF SCQTCALEGC YKDGELVKIA DFYPEDTNTL QKFTFAEQSV SKLRVSFLNS
TDFFGRITLY HLDVLG