ID   NRDH_ECOL6              Reviewed;          81 AA.
AC   P0AC66; Q47414;
DT   08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Glutaredoxin-like protein NrdH;
GN   Name=nrdH; OrderedLocusNames=c3226;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: Electron transport system for the ribonucleotide reductase
CC       system NrdEF. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glutaredoxin family. {ECO:0000305}.
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DR   EMBL; AE014075; AAN81678.1; -; Genomic_DNA.
DR   RefSeq; WP_001223227.1; NC_004431.1.
DR   AlphaFoldDB; P0AC66; -.
DR   SMR; P0AC66; -.
DR   STRING; 199310.c3226; -.
DR   EnsemblBacteria; AAN81678; AAN81678; c3226.
DR   GeneID; 67414033; -.
DR   KEGG; ecc:c3226; -.
DR   eggNOG; COG0695; Bacteria.
DR   HOGENOM; CLU_026126_9_0_6; -.
DR   OMA; PACVQCD; -.
DR   BioCyc; ECOL199310:C3226-MON; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0097573; F:glutathione oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   InterPro; IPR011909; GlrX_NrdH.
DR   InterPro; IPR002109; Glutaredoxin.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   Pfam; PF00462; Glutaredoxin; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   TIGRFAMs; TIGR02194; GlrX_NrdH; 1.
DR   PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Electron transport; Redox-active center; Transport.
FT   CHAIN           1..81
FT                   /note="Glutaredoxin-like protein NrdH"
FT                   /id="PRO_0000141640"
FT   DOMAIN          1..81
FT                   /note="Glutaredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00686"
FT   DISULFID        11..14
FT                   /note="Redox-active"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   81 AA;  9139 MW;  6D0878E9CD133137 CRC64;
     MRITIYTRND CVQCHATKRA MENRGFDFEM INVDRVPEAA EALRAQGFRQ LPVVIAGDLS
     WSGFRPDMIN RLHPAPHAAS A