ID   NRDH_LACLM              Reviewed;          72 AA.
AC   Q48708; A2RLE9;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Glutaredoxin-like protein NrdH;
GN   Name=nrdH; OrderedLocusNames=llmg_1541;
OS   Lactococcus lactis subsp. cremoris (strain MG1363).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus; Lactococcus cremoris subsp. cremoris.
OX   NCBI_TaxID=416870;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-40.
RX   PubMed=8621514; DOI=10.1074/jbc.271.15.8779;
RA   Jordan A., Pontis E., Aaslund F., Hellman U., Gibert I., Reichard P.;
RT   "The ribonucleotide reductase system of Lactococcus lactis.
RT   Characterization of an NrdEF enzyme and a new electron transport protein.";
RL   J. Biol. Chem. 271:8779-8785(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MG1363;
RX   PubMed=17307855; DOI=10.1128/jb.01768-06;
RA   Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C.,
RA   Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P.,
RA   van Sinderen D., Kok J.;
RT   "The complete genome sequence of the lactic acid bacterial paradigm
RT   Lactococcus lactis subsp. cremoris MG1363.";
RL   J. Bacteriol. 189:3256-3270(2007).
CC   -!- FUNCTION: Electron transport system for the ribonucleotide reductase
CC       system NrdEF.
CC   -!- SIMILARITY: Belongs to the glutaredoxin family. {ECO:0000305}.
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DR   EMBL; X92690; CAA63372.1; -; Genomic_DNA.
DR   EMBL; AM406671; CAL98116.1; -; Genomic_DNA.
DR   RefSeq; WP_011675987.1; NZ_WJVF01000002.1.
DR   AlphaFoldDB; Q48708; -.
DR   SMR; Q48708; -.
DR   STRING; 416870.llmg_1541; -.
DR   EnsemblBacteria; CAL98116; CAL98116; llmg_1541.
DR   GeneID; 61109282; -.
DR   KEGG; llm:llmg_1541; -.
DR   eggNOG; COG0695; Bacteria.
DR   HOGENOM; CLU_026126_9_0_9; -.
DR   OMA; PACVQCD; -.
DR   PhylomeDB; Q48708; -.
DR   BioCyc; LLAC416870:LLMG_RS07750-MON; -.
DR   Proteomes; UP000000364; Chromosome.
DR   GO; GO:0097573; F:glutathione oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   InterPro; IPR011909; GlrX_NrdH.
DR   InterPro; IPR002109; Glutaredoxin.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   Pfam; PF00462; Glutaredoxin; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   TIGRFAMs; TIGR02194; GlrX_NrdH; 1.
DR   PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Electron transport;
KW   Redox-active center; Transport.
FT   CHAIN           1..72
FT                   /note="Glutaredoxin-like protein NrdH"
FT                   /id="PRO_0000141644"
FT   DOMAIN          1..72
FT                   /note="Glutaredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00686"
FT   DISULFID        10..13
FT                   /note="Redox-active"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        19
FT                   /note="W -> C (in Ref. 1; AA sequence)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   72 AA;  8302 MW;  DF812C8F5BABC00B CRC64;
     MVTVYSKNNC MQCKMVKKWL SEHEIAFNEI NIDEQPEFVE KVIEMGFRAA PVITKDDFAF
     SGFRPSELAK LA