NRDH_SALTY
ID NRDH_SALTY Reviewed; 81 AA.
AC Q56108;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Glutaredoxin-like protein NrdH;
GN Name=nrdH; OrderedLocusNames=STM2805;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LT2;
RX PubMed=8820648; DOI=10.1046/j.1365-2958.1996.424950.x;
RA Jordan A., Aragall E., Gibert I., Barbe J.;
RT "Promoter identification and expression analysis of Salmonella typhimurium
RT and Escherichia coli nrdEF operons encoding one of two class I
RT ribonucleotide reductases present in both bacteria.";
RL Mol. Microbiol. 19:777-790(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Electron transport system for the ribonucleotide reductase
CC system NrdEF.
CC -!- SIMILARITY: Belongs to the glutaredoxin family. {ECO:0000305}.
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DR EMBL; X73226; CAA51697.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL21690.1; -; Genomic_DNA.
DR RefSeq; NP_461731.1; NC_003197.2.
DR RefSeq; WP_000028870.1; NC_003197.2.
DR AlphaFoldDB; Q56108; -.
DR SMR; Q56108; -.
DR STRING; 99287.STM2805; -.
DR PaxDb; Q56108; -.
DR EnsemblBacteria; AAL21690; AAL21690; STM2805.
DR GeneID; 1254328; -.
DR KEGG; stm:STM2805; -.
DR PATRIC; fig|99287.12.peg.2963; -.
DR HOGENOM; CLU_026126_9_0_6; -.
DR OMA; PACVQCD; -.
DR PhylomeDB; Q56108; -.
DR BioCyc; SENT99287:STM2805-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0009055; F:electron transfer activity; IBA:GO_Central.
DR GO; GO:0097573; F:glutathione oxidoreductase activity; IEA:InterPro.
DR GO; GO:0045454; P:cell redox homeostasis; IBA:GO_Central.
DR InterPro; IPR011909; GlrX_NrdH.
DR InterPro; IPR002109; Glutaredoxin.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR Pfam; PF00462; Glutaredoxin; 1.
DR SUPFAM; SSF52833; SSF52833; 1.
DR TIGRFAMs; TIGR02194; GlrX_NrdH; 1.
DR PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond; Electron transport; Redox-active center;
KW Reference proteome; Transport.
FT CHAIN 1..81
FT /note="Glutaredoxin-like protein NrdH"
FT /id="PRO_0000141641"
FT DOMAIN 1..81
FT /note="Glutaredoxin"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00686"
FT DISULFID 11..14
FT /note="Redox-active"
FT /evidence="ECO:0000250"
SQ SEQUENCE 81 AA; 9076 MW; 5A8D0ADBBC9AECEA CRC64;
MSITIYTRNN CVQCHATKRA MESRGFEFEM VNVDLVPDAA DTLRAQGFRQ LPVVMAGDLS
WSGFRPDMIN RLHPTPHAAN A