ID   NRDR_PARMW              Reviewed;         160 AA.
AC   Q7U4S9;
DT   15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Transcriptional repressor NrdR;
GN   Name=nrdR; OrderedLocusNames=SYNW1984;
OS   Parasynechococcus marenigrum (strain WH8102).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC   Parasynechococcus; Parasynechococcus marenigrum.
OX   NCBI_TaxID=84588;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WH8102;
RX   PubMed=12917641; DOI=10.1038/nature01943;
RA   Palenik B., Brahamsha B., Larimer F.W., Land M.L., Hauser L., Chain P.,
RA   Lamerdin J.E., Regala W., Allen E.E., McCarren J., Paulsen I.T.,
RA   Dufresne A., Partensky F., Webb E.A., Waterbury J.;
RT   "The genome of a motile marine Synechococcus.";
RL   Nature 424:1037-1042(2003).
CC   -!- FUNCTION: Negatively regulates transcription of bacterial
CC       ribonucleotide reductase nrd genes and operons by binding to NrdR-
CC       boxes. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NrdR family. {ECO:0000305}.
CC   -!- CAUTION: Lacks the conserved Cys in position 6 which is part of a zinc-
CC       finger along with Cys-3, Cys 31 and Cys-34. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BX569694; CAE08499.1; -; Genomic_DNA.
DR   RefSeq; WP_011128842.1; NC_005070.1.
DR   AlphaFoldDB; Q7U4S9; -.
DR   SMR; Q7U4S9; -.
DR   STRING; 84588.SYNW1984; -.
DR   EnsemblBacteria; CAE08499; CAE08499; SYNW1984.
DR   KEGG; syw:SYNW1984; -.
DR   eggNOG; COG1327; Bacteria.
DR   HOGENOM; CLU_108412_0_0_3; -.
DR   OMA; YRFTTYE; -.
DR   OrthoDB; 1551627at2; -.
DR   Proteomes; UP000001422; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00440; NrdR; 1.
DR   InterPro; IPR005144; ATP-cone_dom.
DR   InterPro; IPR003796; RNR_NrdR-like.
DR   PANTHER; PTHR30455; PTHR30455; 1.
DR   Pfam; PF03477; ATP-cone; 1.
DR   TIGRFAMs; TIGR00244; TIGR00244; 1.
DR   PROSITE; PS51161; ATP_CONE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA-binding; Nucleotide-binding; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..160
FT                   /note="Transcriptional repressor NrdR"
FT                   /id="PRO_0000182369"
FT   DOMAIN          49..139
FT                   /note="ATP-cone"
SQ   SEQUENCE   160 AA;  18173 MW;  34438C32E9575A62 CRC64;
     MQCPSYQNTD SRVLESRAAD GGRSVRRRRE CLNCEFRFTT YERVETVPIT VIKRNGNREI
     FSRSKLLHGL NRACEKTGLD ASRLETLVEE LELKLQQRSG REVSSAEIGE LVLVELKQMS
     EVAYIRFASV YRQFQGIDDF VSTLETMNRK AGPGHLAAVG