ID   NRFA_PENUR              Reviewed;         865 AA.
AC   Q92269;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Nitrogen regulatory protein nrfA;
GN   Name=nrfA;
OS   Penicillium urticae.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=29844;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=NRRL 2159A;
RA   Ellis C.M.;
RT   "Regulation of polyketide gene expression: the isolation and function of
RT   nitrogen regulatory factor nrfA from Penicillium urticae.";
RL   Thesis (1996), University of Calgary, Canada.
CC   -!- FUNCTION: Major nitrogen regulatory protein.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
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DR   EMBL; U53137; AAB17740.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q92269; -.
DR   SMR; Q92269; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   CDD; cd00202; ZnF_GATA; 1.
DR   Gene3D; 3.30.50.10; -; 1.
DR   InterPro; IPR013860; AreA_GATA.
DR   InterPro; IPR011420; AreA_N.
DR   InterPro; IPR039355; Transcription_factor_GATA.
DR   InterPro; IPR000679; Znf_GATA.
DR   InterPro; IPR013088; Znf_NHR/GATA.
DR   PANTHER; PTHR10071; PTHR10071; 1.
DR   Pfam; PF07573; AreA_N; 1.
DR   Pfam; PF08550; DUF1752; 1.
DR   Pfam; PF00320; GATA; 1.
DR   PRINTS; PR00619; GATAZNFINGER.
DR   SMART; SM00401; ZnF_GATA; 1.
DR   PROSITE; PS00344; GATA_ZN_FINGER_1; 1.
DR   PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
PE   4: Predicted;
KW   Activator; DNA-binding; Metal-binding; Nitrate assimilation; Nucleus;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..865
FT                   /note="Nitrogen regulatory protein nrfA"
FT                   /id="PRO_0000083469"
FT   ZN_FING         665..689
FT                   /note="GATA-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00094"
FT   REGION          1..75
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          115..140
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          177..227
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          557..605
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          617..663
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          713..854
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        34..53
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        633..648
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        713..764
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        796..811
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   865 AA;  92407 MW;  CC901BED187D8EEF CRC64;
     MEGIHHGGHG GARPSQSMAF PGFDADSHMM SDDFTFDSPF SSSGSSNAND GVLGNSIFPE
     WTNGAPRGES PDEMQRKDPL AAQIWKLYTR TKSQLPNQER MENLTWRMMA MNLKRKEREQ
     QEREQQARAS ETVSPAPSGI EMRISDQVSS AGPDLSHDMN LDGTSDAMNL DDFIIPFDSP
     AEHPSHPSAD RQFTATPTGS IPIKSRKDAM MEQSTAASFP RAPQDQRTNS EFGYVARRVR
     KTSVDERQFF AGLSVPTRKR PAEASPQVPP VSNAIVAALG IVSGLPDYSL DHPPSAFALP
     GNGTVGPRRP QHHHTHSNIP YGLDTYGLNE DHGINSAGPY QQNFHFSPSE SPMTAGNPFS
     RLYTQTPLAS SLNSTEFFSP PPSGYQSTVS TPQPIYEGEQ SIFFSDAPSA ESHSQRRIPN
     YIQQRQSNLS ASLQPRYMYN MNGDSHQGNA VTGPPTTHVS GFSVPQPQHV NPAQVLGHGE
     FSTTAPATSM FTFGGDSDNE DDDGNFERGR MTMPNDFASM DESGDMSAGL HWDGGFPGSV
     QSLPGFSAQH RKHVTIGSTD MMDGPPEWNQ GGTLGRGHGS VASVSDVRNQ NQDPRRYGKV
     PRTASTPNAA ALLRQSLNGS ASGPPTNHPS PSTPPESGLS SAVPSRPGSP GGSKNGDPNA
     GPTTCTNCFT QTTPLWRRNP EGQPLCNACG LFLKLHGVVR PLSLKTDVIK KRNRSSANTL
     AVGTSRSSKK SSRKNSIQHA PSTSISSRIN TSESPPSMTG SNTLGKPGVV PIAAAPPKSG
     PPAGVAQGRA GVQVAPRRQR RLEKAPIGSD QDPDDSPKSA APTSRSKVVP LAPAMAPPAA
     ANPANHSIAG GQGASQEWEW LTMSL