ID   NRFD_HAEIN              Reviewed;         321 AA.
AC   P45014;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Protein NrfD homolog;
GN   Name=nrfD; OrderedLocusNames=HI_1066;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Probably involved in the transfer of electrons from the
CC       quinone pool to the type-c cytochromes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NrfD family. {ECO:0000305}.
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DR   EMBL; L42023; AAC22724.1; -; Genomic_DNA.
DR   PIR; I64180; I64180.
DR   RefSeq; NP_439224.1; NC_000907.1.
DR   RefSeq; WP_005693393.1; NC_000907.1.
DR   AlphaFoldDB; P45014; -.
DR   SMR; P45014; -.
DR   STRING; 71421.HI_1066; -.
DR   EnsemblBacteria; AAC22724; AAC22724; HI_1066.
DR   KEGG; hin:HI_1066; -.
DR   PATRIC; fig|71421.8.peg.1110; -.
DR   eggNOG; COG3301; Bacteria.
DR   HOGENOM; CLU_045348_1_2_6; -.
DR   OMA; QFNSVMS; -.
DR   PhylomeDB; P45014; -.
DR   BioCyc; HINF71421:G1GJ1-1102-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   InterPro; IPR017566; NrfD.
DR   InterPro; IPR005614; NrfD_fam.
DR   Pfam; PF03916; NrfD; 1.
DR   TIGRFAMs; TIGR03148; cyt_nit_nrfD; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..321
FT                   /note="Protein NrfD homolog"
FT                   /id="PRO_0000159323"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        224..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        259..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        293..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   321 AA;  35944 MW;  1D0ECFA241B5EB64 CRC64;
     MTLDYPVPFH TPNLVWDYTI AIYLFLLGIS SGAVQLAIAY KRSNKLENLS QNWIIRSGVI
     LGSVPTLIGL TLLIFHLTRP WTFWKLMFNY QFNSVMSMGV MLFQIYMLFL VIWGVVIFKK
     EIEALINRFI PKLQFVMKLI GIAERIVSPV EVILFILAAV LGAYTGFLLS ALISYPMLNN
     PVLPALFLAS GTSSGIAATF LIILIAGKLK GDSHESHFIH KFEVPIMVTE LGLIVCFFVG
     LHFGGGQKTV ALHNALSGFW GVVFWVGVLI IGILIPLIAN MFVNDRLKYN RNFIILVSIF
     DLIGVFCLRF FILYAGQLTV A