NRH2_ORYSJ
ID NRH2_ORYSJ Reviewed; 171 AA.
AC Q5QM06;
DT 07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT 04-JAN-2005, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=NRR repressor homolog 2 {ECO:0000305};
GN Name=RH2 {ECO:0000303|PubMed:22353606};
GN OrderedLocusNames=Os01g0508500 {ECO:0000312|EMBL:BAF05073.1},
GN LOC_Os01g32460 {ECO:0000305};
GN ORFNames=OsJ_01957 {ECO:0000312|EMBL:EEE54666.1},
GN P0455H03.9 {ECO:0000312|EMBL:BAD73539.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP FUNCTION, INTERACTION WITH NPR1/NH1, AND MUTAGENESIS OF 100-A-V-101.
RX PubMed=22353606; DOI=10.1186/1746-4811-8-6;
RA Chern M., Bai W., Sze-To W.H., Canlas P.E., Bartley L.E., Ronald P.C.;
RT "A rice transient assay system identifies a novel domain in NRR required
RT for interaction with NH1/OsNPR1 and inhibition of NH1-mediated
RT transcriptional activation.";
RL Plant Methods 8:6-6(2012).
RN [8]
RP INTERACTION WITH NPR1/NH1 AND NPR3/NH3.
RX PubMed=24919709; DOI=10.1186/1471-2164-15-461;
RA Chern M., Bai W., Ruan D., Oh T., Chen X., Ronald P.C.;
RT "Interaction specificity and coexpression of rice NPR1 homologs 1 and 3
RT (NH1 and NH3), TGA transcription factors and negative regulator of
RT resistance (NRR) proteins.";
RL BMC Genomics 15:461-461(2014).
CC -!- FUNCTION: Binds to and weakly represses NPR1/NH1-mediated
CC transcriptional activation of LG2 in vitro.
CC {ECO:0000269|PubMed:22353606}.
CC -!- SUBUNIT: Interacts with NPR1/NH1 (PubMed:22353606, PubMed:24919709).
CC Interacts with NPR3/NH3 (PubMed:24919709).
CC {ECO:0000269|PubMed:22353606, ECO:0000269|PubMed:24919709}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q5ZEF1}.
CC -!- SIMILARITY: Belongs to the NPR1-interactor family.
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DR EMBL; AP003435; BAD73539.1; -; Genomic_DNA.
DR EMBL; AP008207; BAF05073.1; -; Genomic_DNA.
DR EMBL; AP014957; BAS72363.1; -; Genomic_DNA.
DR EMBL; CM000138; EEE54666.1; -; Genomic_DNA.
DR EMBL; AK120501; BAH00041.1; -; mRNA.
DR RefSeq; XP_015633794.1; XM_015778308.1.
DR AlphaFoldDB; Q5QM06; -.
DR STRING; 4530.OS01T0508500-01; -.
DR PaxDb; Q5QM06; -.
DR PRIDE; Q5QM06; -.
DR EnsemblPlants; Os01t0508500-01; Os01t0508500-01; Os01g0508500.
DR GeneID; 4324018; -.
DR Gramene; Os01t0508500-01; Os01t0508500-01; Os01g0508500.
DR KEGG; osa:4324018; -.
DR HOGENOM; CLU_1654937_0_0_1; -.
DR OMA; EMADFEC; -.
DR OrthoDB; 1644699at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000007752; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0010112; P:regulation of systemic acquired resistance; IEA:InterPro.
DR InterPro; IPR031425; NPR1/NH1-interacting.
DR PANTHER; PTHR33669; PTHR33669; 1.
DR Pfam; PF15699; NPR1_interact; 1.
PE 1: Evidence at protein level;
KW Nucleus; Plant defense; Reference proteome.
FT CHAIN 1..171
FT /note="NRR repressor homolog 2"
FT /id="PRO_0000437010"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 65..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 119..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..143
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MUTAGEN 100..101
FT /note="AV->ED: Strongly increases NPR1/NH1 binding
FT efficiency and repression of NPR1/NH1-mediated
FT transcriptional activation of LG2."
FT /evidence="ECO:0000269|PubMed:22353606"
SQ SEQUENCE 171 AA; 18125 MW; 65039F5F2F1C3CD5 CRC64;
MEARLSTGEK TKKMATTSRP SSPLPPEEET AAETTTSEEE EQQQMERFYA LVANVRALRA
MFKEAALPSC REDDVSGGGG GEQRQKRPRA APWRPAFEMA VFECGGGGGT TTDDIEAATT
KGQDGNCKKG KRSEANAAAE EDKGEVIEGK PVAIAIVADG PGKSTTMPDS N
