NRIP3_MOUSE
ID NRIP3_MOUSE Reviewed; 240 AA.
AC Q9JJR9; Q8BUN8;
DT 29-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Nuclear receptor-interacting protein 3;
GN Name=Nrip3; Synonyms=D7H11orf14;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=11528127; DOI=10.1159/000056999;
RA Amid C., Bahr A., Mujica A., Sampson N., Bikar S.E., Winterpacht A.,
RA Zabel B., Hankeln T., Schmidt E.R.;
RT "Comparative genomic sequencing reveals a strikingly similar architecture
RT of a conserved syntenic region on human chromosome 11p15.3 (including gene
RT ST5) and mouse chromosome 7.";
RL Cytogenet. Cell Genet. 93:284-290(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Hippocampus;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
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DR EMBL; AJ400878; CAB92294.1; -; Genomic_DNA.
DR EMBL; AK083130; BAC38775.1; -; mRNA.
DR CCDS; CCDS21739.1; -.
DR RefSeq; NP_065635.1; NM_020610.1.
DR AlphaFoldDB; Q9JJR9; -.
DR SMR; Q9JJR9; -.
DR BioGRID; 219504; 27.
DR IntAct; Q9JJR9; 27.
DR STRING; 10090.ENSMUSP00000033331; -.
DR MEROPS; A28.002; -.
DR iPTMnet; Q9JJR9; -.
DR PhosphoSitePlus; Q9JJR9; -.
DR MaxQB; Q9JJR9; -.
DR PaxDb; Q9JJR9; -.
DR PRIDE; Q9JJR9; -.
DR ProteomicsDB; 293971; -.
DR Antibodypedia; 24183; 222 antibodies from 26 providers.
DR DNASU; 78593; -.
DR Ensembl; ENSMUST00000033331; ENSMUSP00000033331; ENSMUSG00000034825.
DR GeneID; 78593; -.
DR KEGG; mmu:78593; -.
DR UCSC; uc009jef.1; mouse.
DR CTD; 56675; -.
DR MGI; MGI:1925843; Nrip3.
DR VEuPathDB; HostDB:ENSMUSG00000034825; -.
DR eggNOG; KOG0012; Eukaryota.
DR GeneTree; ENSGT00950000182999; -.
DR HOGENOM; CLU_087166_1_0_1; -.
DR InParanoid; Q9JJR9; -.
DR OrthoDB; 1182441at2759; -.
DR PhylomeDB; Q9JJR9; -.
DR TreeFam; TF333421; -.
DR BioGRID-ORCS; 78593; 0 hits in 75 CRISPR screens.
DR ChiTaRS; Nrip3; mouse.
DR PRO; PR:Q9JJR9; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q9JJR9; protein.
DR Bgee; ENSMUSG00000034825; Expressed in medial dorsal nucleus of thalamus and 144 other tissues.
DR ExpressionAtlas; Q9JJR9; baseline and differential.
DR Genevisible; Q9JJR9; MM.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd05480; NRIP_C; 1.
DR Gene3D; 2.40.70.10; -; 1.
DR InterPro; IPR033821; NRIP_C.
DR InterPro; IPR019103; Peptidase_aspartic_DDI1-type.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR Pfam; PF09668; Asp_protease; 1.
DR SUPFAM; SSF50630; SSF50630; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..240
FT /note="Nuclear receptor-interacting protein 3"
FT /id="PRO_0000057954"
FT CONFLICT 68
FT /note="L -> F (in Ref. 2; BAC38775)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 240 AA; 26879 MW; 05D527AACF6C562A CRC64;
MFYSGLLTEG GRKETDMREA ASLRQQRRMK QAVQFIHKDS ADLLPLDGLK KLGSSKDTQP
HNILQRRLME TNLSKLRSTR VPWASKTNKF NQAKSEGLKK CEDEDMILVS CQCAGKDVKA
LVDTGCQYNL ISSACVDRLG LKDHVKSHKH EGEKLSLPRH LKVVGQIEHL MITVGSLRLD
CQAAVVDDNE KSLSLGLQTL RSLKCIINLD KHRLIVGKTD KEEIPFVETV SVNDDNTSEA
