NRM1_CANGA
ID NRM1_CANGA Reviewed; 293 AA.
AC Q6FQJ4;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 70.
DE RecName: Full=Transcription factor NRM1;
GN Name=NRM1; OrderedLocusNames=CAGL0I05764g;
OS Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS Y-65) (Yeast) (Torulopsis glabrata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC Nakaseomyces/Candida clade.
OX NCBI_TaxID=284593;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: Negative regulatory component of the MBF complex involved in
CC cell-cycle-dependent transcription. {ECO:0000250}.
CC -!- SUBUNIT: Component of the MBF complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the WHI5/NRM1 family. {ECO:0000305}.
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DR EMBL; CR380955; CAG60437.1; -; Genomic_DNA.
DR RefSeq; XP_447500.1; XM_447500.1.
DR AlphaFoldDB; Q6FQJ4; -.
DR STRING; 5478.XP_447500.1; -.
DR EnsemblFungi; CAG60437; CAG60437; CAGL0I05764g.
DR GeneID; 2889344; -.
DR KEGG; cgr:CAGL0I05764g; -.
DR CGD; CAL0129746; CAGL0I05764g.
DR VEuPathDB; FungiDB:CAGL0I05764g; -.
DR eggNOG; ENOG502S72A; Eukaryota.
DR HOGENOM; CLU_098759_0_0_1; -.
DR InParanoid; Q6FQJ4; -.
DR OMA; TIERNSC; -.
DR Proteomes; UP000002428; Chromosome I.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030907; C:MBF transcription complex; IEA:EnsemblFungi.
DR GO; GO:0140297; F:DNA-binding transcription factor binding; IEA:EnsemblFungi.
DR GO; GO:0071930; P:negative regulation of transcription involved in G1/S transition of mitotic cell cycle; IEA:EnsemblFungi.
DR InterPro; IPR013734; TF_Nrm1/Whi5.
DR Pfam; PF08528; Whi5; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleus; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..293
FT /note="Transcription factor NRM1"
FT /id="PRO_0000320391"
FT REGION 239..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 293 AA; 32747 MW; 6F5CCC8962B56A54 CRC64;
MVMSLERLPL QEYTKSAMNN LATSGPVIMT SLTEGSSLSK NSVGMGLGMK LPSIHSLINQ
KNSYNPFQTT LHSKSFSVGD PIKANNSKPL GVTLTSTDSN KRLNTSISAL LTDNKSPGKA
NKPETEKETM NHLVQEDTVD KAHYTELSKK LQIRLQLAYY KYRTKQEHVK FNELKALHSS
KPKKASKKNT KRRKLVVSHG NFKTPAKRKE HKLYTTNTHN LQDVSTDISM SSSTSSLMSK
RDSSLQFHDS NDTTNDFTTP IRNANKRHLG QKQDTPMSVK AAKSLIFLYS SKV