ID   NRM1_KLULA              Reviewed;         221 AA.
AC   Q6CL21;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Transcription factor NRM1;
GN   Name=NRM1; OrderedLocusNames=KLLA0F06358g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Negative regulatory component of the MBF complex involved in
CC       cell-cycle-dependent transcription. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the MBF complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WHI5/NRM1 family. {ECO:0000305}.
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DR   EMBL; CR382126; CAG98076.1; -; Genomic_DNA.
DR   RefSeq; XP_455368.1; XM_455368.1.
DR   AlphaFoldDB; Q6CL21; -.
DR   EnsemblFungi; CAG98076; CAG98076; KLLA0_F06358g.
DR   GeneID; 2895030; -.
DR   KEGG; kla:KLLA0_F06358g; -.
DR   HOGENOM; CLU_1250843_0_0_1; -.
DR   InParanoid; Q6CL21; -.
DR   Proteomes; UP000000598; Chromosome F.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR013734; TF_Nrm1/Whi5.
DR   Pfam; PF08528; Whi5; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..221
FT                   /note="Transcription factor NRM1"
FT                   /id="PRO_0000320392"
FT   REGION          21..48
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   221 AA;  24608 MW;  019AFD6ACBE6A094 CRC64;
     MSVRLPLGQI SSSKLNVLSQ ENKLHQGKRS VRPQLNTPSN SPSTESFNNS EISLASVLNT
     QTSSSQFYST PPQALHDVKE RINNELTEKN SKLTDENILR LRSRVQLAYY KYRTKQVHLK
     FSEIVSRKKQ SANKIRKPEN DRKSRKLAGL NPAIEATSRT NNNNNGTSNL AVCSQQHIQC
     ITPEKRYPAK PYASTSAISS GYTPVSVKAA KSLLQMFSTG A