NRM1_YEAS7
ID NRM1_YEAS7 Reviewed; 249 AA.
AC A6ZS83;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-SEP-2007, sequence version 1.
DT 03-AUG-2022, entry version 45.
DE RecName: Full=Transcription factor NRM1;
DE AltName: Full=Negative regulator of MBF targets 1;
GN Name=NRM1; ORFNames=SCY_4794;
OS Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=307796;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YJM789;
RX PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA Steinmetz L.M.;
RT "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT strain YJM789.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC -!- FUNCTION: Negative regulatory component of the MBF complex involved in
CC cell-cycle-dependent transcription. {ECO:0000250}.
CC -!- SUBUNIT: The MBF complex is composed of at least SWI6, MBP1 and NRM1.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- INDUCTION: During G1 phase of the cell cycle. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the WHI5/NRM1 family. {ECO:0000305}.
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DR EMBL; AAFW02000067; EDN62815.1; -; Genomic_DNA.
DR AlphaFoldDB; A6ZS83; -.
DR SMR; A6ZS83; -.
DR PRIDE; A6ZS83; -.
DR EnsemblFungi; EDN62815; EDN62815; SCY_4794.
DR HOGENOM; CLU_098759_0_0_1; -.
DR Proteomes; UP000007060; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR013734; TF_Nrm1/Whi5.
DR Pfam; PF08528; Whi5; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleus; Phosphoprotein; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..249
FT /note="Transcription factor NRM1"
FT /id="PRO_0000320394"
FT REGION 208..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 145
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P53718"
SQ SEQUENCE 249 AA; 27564 MW; F776CC26B92C8C46 CRC64;
MSIMKQRLPL GEFSSSKINK LAIANIADAS EPRNHGENNV GTVCLPSIKS LMVSPEVYEN
TKSLPVPLMR SSGGGMACAS KSSCQDGIST KTTSRDYSEL SKKLQIRLQF AYYKYKTKQT
DKNFTDLKSK HSITRPSKVA THSKSEPLTR RRKLVLSQGH YKTPARSKIK TPSSICSHDN
TSSFTSFRGV SESSSTTADM NVADTTTPIR NNINTKHSNS HNRTLYQRQE TPTSIKAAKS
LIHLFTSNQ