ID   NRM_BOVIN               Reviewed;         262 AA.
AC   Q32LM8;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Nurim;
DE   AltName: Full=Nuclear envelope membrane protein;
DE   AltName: Full=Nuclear rim protein;
GN   Name=NRM;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- INTERACTION:
CC       Q32LM8; Q28181: CNGB1; NbExp=4; IntAct=EBI-7079707, EBI-6979031;
CC   -!- SUBCELLULAR LOCATION: Nucleus inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the nurim family. {ECO:0000305}.
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DR   EMBL; BC109506; AAI09507.1; -; mRNA.
DR   RefSeq; NP_001032685.1; NM_001037596.2.
DR   AlphaFoldDB; Q32LM8; -.
DR   IntAct; Q32LM8; 1.
DR   MINT; Q32LM8; -.
DR   STRING; 9913.ENSBTAP00000035763; -.
DR   PaxDb; Q32LM8; -.
DR   Ensembl; ENSBTAT00000035896; ENSBTAP00000035763; ENSBTAG00000006966.
DR   GeneID; 511167; -.
DR   KEGG; bta:511167; -.
DR   CTD; 11270; -.
DR   VEuPathDB; HostDB:ENSBTAG00000006966; -.
DR   VGNC; VGNC:49560; NRM.
DR   eggNOG; ENOG502RS62; Eukaryota.
DR   GeneTree; ENSGT00390000008146; -.
DR   HOGENOM; CLU_083708_1_0_1; -.
DR   InParanoid; Q32LM8; -.
DR   OMA; WSIWFPL; -.
DR   OrthoDB; 1048330at2759; -.
DR   TreeFam; TF324853; -.
DR   Proteomes; UP000009136; Chromosome 23.
DR   Bgee; ENSBTAG00000006966; Expressed in semen and 105 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005635; C:nuclear envelope; ISS:UniProtKB.
DR   GO; GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0031965; C:nuclear membrane; IBA:GO_Central.
DR   InterPro; IPR033580; Nurim-like.
DR   PANTHER; PTHR31040; PTHR31040; 1.
PE   1: Evidence at protein level;
KW   Membrane; Nucleus; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..262
FT                   /note="Nurim"
FT                   /id="PRO_0000299394"
FT   TOPO_DOM        1..4
FT                   /note="Nuclear"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        5..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        29..58
FT                   /note="Perinuclear space"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        81..97
FT                   /note="Nuclear"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        115..133
FT                   /note="Perinuclear space"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        165..191
FT                   /note="Nuclear"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        192..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        211..216
FT                   /note="Perinuclear space"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        217..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        235..262
FT                   /note="Nuclear"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   262 AA;  29638 MW;  F44FF93ECE4352A4 CRC64;
     MAPALLLIPA ALASFILAFG TGVEFVRFTS LRPLLGRISE SGSPDARQGW LAALQDQSIL
     VPLVWDLGLL LLFVGQHSLM ATETVKEWMS RYFGVLQRSL YVACTALALQ LVMRYWEPVP
     RGPVLWETRT EPWATWVPLL CFVLHVISWL LIFSILLVFD YAELMGLKQV YYHVLGLGEP
     LALKSPRALR LFSHLRHPVC VELLTVLWVV PTLGTDRLLL ALLLTLYLGL AHGLDQHDLR
     YLRAQLQRKL HLLSRPQDGE AE