ID   NRM_MACMU               Reviewed;         262 AA.
AC   Q5TM67;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Nurim;
DE   AltName: Full=Nuclear envelope membrane protein;
DE   AltName: Full=Nuclear rim protein;
GN   Name=NRM;
OS   Macaca mulatta (Rhesus macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9544;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15269276; DOI=10.1093/molbev/msh216;
RA   Kulski J.K., Anzai T., Shiina T., Inoko H.;
RT   "Rhesus macaque class I duplicon structures, organization, and evolution
RT   within the alpha block of the major histocompatibility complex.";
RL   Mol. Biol. Evol. 21:2079-2091(2004).
CC   -!- SUBCELLULAR LOCATION: Nucleus inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the nurim family. {ECO:0000305}.
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DR   EMBL; AB128049; BAD69759.1; -; Genomic_DNA.
DR   RefSeq; NP_001098637.1; NM_001105167.1.
DR   AlphaFoldDB; Q5TM67; -.
DR   STRING; 9544.ENSMMUP00000022618; -.
DR   Ensembl; ENSMMUT00000024173; ENSMMUP00000022618; ENSMMUG00000017194.
DR   GeneID; 713998; -.
DR   KEGG; mcc:713998; -.
DR   CTD; 11270; -.
DR   VEuPathDB; HostDB:ENSMMUG00000017194; -.
DR   VGNC; VGNC:75531; NRM.
DR   eggNOG; ENOG502RS62; Eukaryota.
DR   GeneTree; ENSGT00390000008146; -.
DR   InParanoid; Q5TM67; -.
DR   OrthoDB; 1048330at2759; -.
DR   Proteomes; UP000006718; Chromosome 4.
DR   Bgee; ENSMMUG00000017194; Expressed in fibroblast and 20 other tissues.
DR   ExpressionAtlas; Q5TM67; baseline.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005635; C:nuclear envelope; ISS:UniProtKB.
DR   GO; GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR033580; Nurim-like.
DR   PANTHER; PTHR31040; PTHR31040; 1.
PE   3: Inferred from homology;
KW   Membrane; Nucleus; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..262
FT                   /note="Nurim"
FT                   /id="PRO_0000299396"
FT   TOPO_DOM        1..4
FT                   /note="Nuclear"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        5..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        29..58
FT                   /note="Perinuclear space"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        81..97
FT                   /note="Nuclear"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        115..133
FT                   /note="Perinuclear space"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        165..191
FT                   /note="Nuclear"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        192..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        211..216
FT                   /note="Perinuclear space"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        217..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        235..262
FT                   /note="Nuclear"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   262 AA;  29347 MW;  C7AA5EB8330C3C17 CRC64;
     MAPALLLVPA ALASFILAFG TGVEFVRFTS LRPLLGGIPE SGGPDARQGW LAALQDRSIL
     APLAWDLGLL LLFVGQHSLM AAERVKAWTS RYFGVLQRSL YVACTALALQ LVMRYWEPVP
     RGPVLWEAQA EPWATWVPLL CFVLHVISWL LIFSILLVFD YAELMGLKQV YYHVLGLGEP
     LALKSPRALR LFSHLRHPVC VELLTVLWVV PTLGMDRLLL ALLLTLYLGL AHGLDQQDLR
     YLRAQLQRKL HLLSRPQDGE AE