NRM_RAT
ID NRM_RAT Reviewed; 262 AA.
AC Q6MG14;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Nurim;
DE AltName: Full=Nuclear envelope membrane protein;
DE AltName: Full=Nuclear rim protein;
GN Name=Nrm;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Brown Norway;
RX PubMed=15060004; DOI=10.1101/gr.1987704;
RA Hurt P., Walter L., Sudbrak R., Klages S., Mueller I., Shiina T., Inoko H.,
RA Lehrach H., Guenther E., Reinhardt R., Himmelbauer H.;
RT "The genomic sequence and comparative analysis of the rat major
RT histocompatibility complex.";
RL Genome Res. 14:631-639(2004).
CC -!- SUBCELLULAR LOCATION: Nucleus inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the nurim family. {ECO:0000305}.
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DR EMBL; BX883048; CAE84033.1; -; Genomic_DNA.
DR RefSeq; NP_997673.1; NM_212508.2.
DR AlphaFoldDB; Q6MG14; -.
DR BioGRID; 262960; 1.
DR STRING; 10116.ENSRNOP00000001085; -.
DR PaxDb; Q6MG14; -.
DR Ensembl; ENSRNOT00000001085; ENSRNOP00000001085; ENSRNOG00000000818.
DR GeneID; 361791; -.
DR KEGG; rno:361791; -.
DR UCSC; RGD:1302966; rat.
DR CTD; 11270; -.
DR RGD; 1302966; Nrm.
DR eggNOG; ENOG502RS62; Eukaryota.
DR GeneTree; ENSGT00530000064035; -.
DR HOGENOM; CLU_083708_1_0_1; -.
DR InParanoid; Q6MG14; -.
DR OMA; WSIWFPL; -.
DR OrthoDB; 1048330at2759; -.
DR PhylomeDB; Q6MG14; -.
DR TreeFam; TF324853; -.
DR PRO; PR:Q6MG14; -.
DR Proteomes; UP000002494; Chromosome 20.
DR Bgee; ENSRNOG00000000818; Expressed in testis and 19 other tissues.
DR ExpressionAtlas; Q6MG14; baseline and differential.
DR Genevisible; Q6MG14; RN.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005635; C:nuclear envelope; ISS:UniProtKB.
DR GO; GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0031965; C:nuclear membrane; ISO:RGD.
DR InterPro; IPR033580; Nurim-like.
DR PANTHER; PTHR31040; PTHR31040; 1.
PE 3: Inferred from homology;
KW Membrane; Nucleus; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..262
FT /note="Nurim"
FT /id="PRO_0000299400"
FT TOPO_DOM 1..4
FT /note="Nuclear"
FT /evidence="ECO:0000255"
FT TRANSMEM 5..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 29..58
FT /note="Perinuclear space"
FT /evidence="ECO:0000255"
FT TRANSMEM 59..80
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 81..97
FT /note="Nuclear"
FT /evidence="ECO:0000255"
FT TRANSMEM 98..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 115..133
FT /note="Perinuclear space"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..164
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 165..191
FT /note="Nuclear"
FT /evidence="ECO:0000255"
FT TRANSMEM 192..210
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 211..216
FT /note="Perinuclear space"
FT /evidence="ECO:0000255"
FT TRANSMEM 217..234
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 235..262
FT /note="Nuclear"
FT /evidence="ECO:0000255"
SQ SEQUENCE 262 AA; 29382 MW; FEAC40DA59359772 CRC64;
MAPALLLVPA ALASFVLAFG TGVEFVRFTS LRPLLGGIPE SGGPDARHGW LAALQDRSIL
ASLAWDLCLL LLFVVQHSLM ATEAVKAWTS RYFGVLQRSL YVACTALALQ LVMRYWEATP
RGPVLWEARA EPWATWVPLL CFVLHVVSWL LIFSILLVFD YAELMGLKQV YYHVLGLGEP
LSLKSPRALR LFSHLRHPVC VELLTVLWVV PTLGTDRLLL ALLFTLYLGL AHGLDQQDLR
YLRSQLQRKL QLLSRPQDGE AE
