ID   NRM_XENLA               Reviewed;         285 AA.
AC   Q6GNM0;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 48.
DE   RecName: Full=Nurim;
DE   AltName: Full=Nuclear envelope membrane protein;
DE   AltName: Full=Nuclear rim protein;
GN   Name=nrm;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the nurim family. {ECO:0000305}.
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DR   EMBL; BC073486; AAH73486.1; -; mRNA.
DR   RefSeq; NP_001085892.1; NM_001092423.1.
DR   AlphaFoldDB; Q6GNM0; -.
DR   DNASU; 444319; -.
DR   GeneID; 444319; -.
DR   KEGG; xla:444319; -.
DR   CTD; 444319; -.
DR   Xenbase; XB-GENE-865292; nrm.L.
DR   OMA; WSIWFPL; -.
DR   OrthoDB; 1048330at2759; -.
DR   Proteomes; UP000186698; Chromosome 8L.
DR   Bgee; 444319; Expressed in egg cell and 19 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005635; C:nuclear envelope; ISS:UniProtKB.
DR   GO; GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR033580; Nurim-like.
DR   PANTHER; PTHR31040; PTHR31040; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Nucleus; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..285
FT                   /note="Nurim"
FT                   /id="PRO_0000299402"
FT   TOPO_DOM        1..16
FT                   /note="Nuclear"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        17..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        45..74
FT                   /note="Perinuclear space"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        75..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        97..113
FT                   /note="Nuclear"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        114..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        131..149
FT                   /note="Perinuclear space"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        150..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        181..207
FT                   /note="Nuclear"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        208..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        227..232
FT                   /note="Perinuclear space"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        233..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        251..285
FT                   /note="Nuclear"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   285 AA;  32070 MW;  CECE0A0CCD86E7CA CRC64;
     MSANVQVSGQ LSSGPSLPAC IVLSAVSLLC FVAGFGTGAE FVRFLSFGAI FRNISGGLDG
     EIPLTWSEAI RNTQFQCCIG IDIGLLFLFV LQHSLMAWTA VKKNVLHVFG VLQRSIYILC
     TALSLQVLMR FWQPCPHGPY LWNVSSDPWS AWLPLLCALV HTISWLLIFS VLLIFDYAEL
     MGIKQVYYFC LGMGDPLSHK SPRVARLYAH LRHPIYLELL LILWAVPCLP PDRLILAIFF
     TLYLSLVHRL DVQDYAYLRS QLEKKFLLFS REEASAVGGQ IRKNN