ID   NRN1_DANRE              Reviewed;         142 AA.
AC   Q6DGP8;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Neuritin;
DE   Flags: Precursor;
GN   Name=nrn1; ORFNames=zgc:92828;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Modulates postsynaptic dendritic arbor elaboration and
CC       synaptic maturation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-
CC       anchor {ECO:0000305}. Synapse {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the neuritin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC076292; AAH76292.1; -; mRNA.
DR   RefSeq; NP_001002507.1; NM_001002507.2.
DR   AlphaFoldDB; Q6DGP8; -.
DR   STRING; 7955.ENSDARP00000097397; -.
DR   PaxDb; Q6DGP8; -.
DR   GeneID; 436780; -.
DR   KEGG; dre:436780; -.
DR   CTD; 436780; -.
DR   ZFIN; ZDB-GENE-040718-212; nrn1a.
DR   eggNOG; ENOG502RZNR; Eukaryota.
DR   InParanoid; Q6DGP8; -.
DR   OrthoDB; 1469106at2759; -.
DR   PhylomeDB; Q6DGP8; -.
DR   PRO; PR:Q6DGP8; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0046658; C:anchored component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0070161; C:anchoring junction; IEA:UniProtKB-KW.
DR   GO; GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
DR   GO; GO:1990138; P:neuron projection extension; IBA:GO_Central.
DR   InterPro; IPR026144; Neuritin_fam.
DR   PANTHER; PTHR15902; PTHR15902; 1.
DR   Pfam; PF15056; NRN1; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Glycoprotein; GPI-anchor; Lipoprotein; Membrane;
KW   Reference proteome; Signal; Synapse.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..112
FT                   /note="Neuritin"
FT                   /id="PRO_0000262518"
FT   PROPEP          113..142
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000262519"
FT   LIPID           112
FT                   /note="GPI-anchor amidated alanine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   142 AA;  15618 MW;  E49BCC58A99636DF CRC64;
     MGLTLSGRYI SLFLAVQIAY LLQAVRAAGK CGTVFKGFSD CLLQLGENMA NYPQELDEKE
     NLQTICTYWD DFHSCATTAL ADCQEGATDL WEKLKKESRN LDFRGSLFEL CAGGNGAIRS
     SVPFGVTLLI TALSALVTWM QF