NRPB_SOYBN
ID NRPB_SOYBN Reviewed; 330 AA.
AC C6TAQ0;
DT 07-OCT-2020, integrated into UniProtKB/Swiss-Prot.
DT 22-SEP-2009, sequence version 1.
DT 25-MAY-2022, entry version 63.
DE RecName: Full=DCD domain-containing protein NRP-B {ECO:0000305};
DE AltName: Full=N-rich protein B {ECO:0000303|PubMed:18490446};
GN Name=NRP-B {ECO:0000303|PubMed:18490446};
GN ORFNames=GLYMA_05G218500 {ECO:0000312|EMBL:KRH60068.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Cheung F., Xiao Y., Chan A., Moskal W., Town C.D.;
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82;
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [3]
RP INDUCTION.
RX PubMed=18036212; DOI=10.1186/1471-2164-8-431;
RA Irsigler A.S., Costa M.D., Zhang P., Reis P.A., Dewey R.E., Boston R.S.,
RA Fontes E.P.;
RT "Expression profiling on soybean leaves reveals integration of ER- and
RT osmotic-stress pathways.";
RL BMC Genomics 8:431-431(2007).
RN [4]
RP FUNCTION, SUBCELLULAR LOCATION, AND INDUCTION.
RX PubMed=18490446; DOI=10.1074/jbc.m802654200;
RA Costa M.D., Reis P.A., Valente M.A., Irsigler A.S., Carvalho C.M.,
RA Loureiro M.E., Aragao F.J., Boston R.S., Fietto L.G., Fontes E.P.;
RT "A new branch of endoplasmic reticulum stress signaling and the osmotic
RT signal converge on plant-specific asparagine-rich proteins to promote cell
RT death.";
RL J. Biol. Chem. 283:20209-20219(2008).
RN [5]
RP INDUCTION.
RX PubMed=21482825; DOI=10.1074/jbc.m111.233494;
RA Alves M.S., Reis P.A., Dadalto S.P., Faria J.A., Fontes E.P., Fietto L.G.;
RT "A novel transcription factor, ERD15 (Early Responsive to Dehydration 15),
RT connects endoplasmic reticulum stress with an osmotic stress-induced cell
RT death signal.";
RL J. Biol. Chem. 286:20020-20030(2011).
CC -!- FUNCTION: Involved in stress signaling pathway that mediates cell death
CC in response to endoplasmic reticulum (ER) stress and osmotic stress.
CC {ECO:0000269|PubMed:18490446}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:18490446}.
CC -!- INDUCTION: Induced by tunicamycin, azetidine-2-carboxylate (AZC) and
CC osmotic stress (PubMed:18490446, PubMed:18036212). Induced by
CC dithiothreitol (DTT) (PubMed:18490446). Induced by wounding
CC (PubMed:21482825). {ECO:0000269|PubMed:18036212,
CC ECO:0000269|PubMed:18490446, ECO:0000269|PubMed:21482825}.
CC -!- MISCELLANEOUS: Over expression of NRP in protoplasts induces caspase-3-
CC like activity and promotes extensive DNA fragmentation
CC (PubMed:18490446). Transient expression of NRP in planta causes leaf
CC yellowing, chlorophyll loss, malondialdehyde production, ethylene
CC accumulation, and induction of the senescence marker gene CP1
CC (PubMed:18490446). {ECO:0000269|PubMed:18490446}.
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DR EMBL; BT094591; ACU18902.1; -; mRNA.
DR EMBL; CM000838; KRH60068.1; -; Genomic_DNA.
DR RefSeq; NP_001239779.1; NM_001252850.2.
DR AlphaFoldDB; C6TAQ0; -.
DR EnsemblPlants; KRH60068; KRH60068; GLYMA_05G218500.
DR GeneID; 100808989; -.
DR Gramene; KRH60068; KRH60068; GLYMA_05G218500.
DR KEGG; gmx:100808989; -.
DR HOGENOM; CLU_051751_0_0_1; -.
DR OrthoDB; 1210304at2759; -.
DR Proteomes; UP000008827; Chromosome 5.
DR ExpressionAtlas; C6TAQ0; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
DR GO; GO:0034976; P:response to endoplasmic reticulum stress; IMP:UniProtKB.
DR GO; GO:0009414; P:response to water deprivation; IMP:UniProtKB.
DR InterPro; IPR013989; Dev_and_cell_death_domain.
DR InterPro; IPR044832; NRP-like.
DR PANTHER; PTHR46034; PTHR46034; 2.
DR Pfam; PF10539; Dev_Cell_Death; 1.
DR SMART; SM00767; DCD; 1.
DR PROSITE; PS51222; DCD; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Reference proteome; Stress response.
FT CHAIN 1..330
FT /note="DCD domain-containing protein NRP-B"
FT /id="PRO_0000451107"
FT DOMAIN 185..317
FT /note="DCD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00569"
FT REGION 137..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..178
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 330 AA; 37104 MW; BCE9F37C98355D22 CRC64;
MENNNQSFWQ FSDQLRLQAS NLANLSLNDS IWSNNYISKR RDERINFDIK VGGEINSFKS
KDPACDYNDN VNGSLLAMPY NNNNNNNIIL GFGGVGLNGG FNKGIYSKPA FANLNNNINL
NINPKGHKGK VEDELFHPSK SSKKNNNLNK KHGDNNNNDN NKDSKAAGDK RFKTLPPSES
LPRDETIGGY IFVCNNDTMA ENLKRQLFGL PPRYRDSVRA ITPGLPLFLY NYSTHQLHGI
FEAASFGGTN IDPSAWEDKK CPGESRFPAQ VRVITRKTCE PLEEDSFRPI LHHYDGPKFR
LELNVPEALS LLDIFAEQDT FNDAFEALPA
