NRR_ORYSI
ID NRR_ORYSI Reviewed; 131 AA.
AC Q5EN53;
DT 07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 63.
DE RecName: Full=Protein NEGATIVE REGULATOR OF RESISTANCE {ECO:0000303|PubMed:16115061};
DE AltName: Full=NPR1-interactor {ECO:0000312|EMBL:AAW80625.1};
GN Name=NRR {ECO:0000303|PubMed:16115061};
GN ORFNames=OsI_00248 {ECO:0000312|EMBL:EAY72394.1};
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INTERACTION WITH NPR1/NH1,
RP SUBCELLULAR LOCATION, AND MUTAGENESIS OF GLU-39; PHE-40 AND LEU-44.
RC STRAIN=cv. IRBB21;
RX PubMed=16115061; DOI=10.1111/j.1365-313x.2005.02485.x;
RA Chern M., Canlas P.E., Fitzgerald H.A., Ronald P.C.;
RT "Rice NRR, a negative regulator of disease resistance, interacts with
RT Arabidopsis NPR1 and rice NH1.";
RL Plant J. 43:623-635(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [3]
RP INTERACTION WITH NPR1/NH1 AND NPR2/NH2.
RX PubMed=15986920; DOI=10.1094/mpmi-18-0511;
RA Chern M., Fitzgerald H.A., Canlas P.E., Navarre D.A., Ronald P.C.;
RT "Overexpression of a rice NPR1 homolog leads to constitutive activation of
RT defense response and hypersensitivity to light.";
RL Mol. Plant Microbe Interact. 18:511-520(2005).
CC -!- FUNCTION: Acts as negative regulator of disease resistance. Acts on
CC basal resistance, age-related resistance and resistance mediated by the
CC LRR receptor kinase XA21. Plants over-expressing NRR display enhanced
CC susceptibility to the bacterial blight Xanthomonas oryzae pv. oryzae
CC (Xoo). {ECO:0000269|PubMed:16115061}.
CC -!- SUBUNIT: Interacts with NPR1/NH1 (PubMed:16115061, PubMed:15986920).
CC Interacts with NPR2/NH2 (PubMed:15986920).
CC {ECO:0000269|PubMed:15986920, ECO:0000269|PubMed:16115061}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16115061}.
CC -!- SIMILARITY: Belongs to the NPR1-interactor family.
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DR EMBL; AY846391; AAW80625.1; -; mRNA.
DR EMBL; CM000126; EAY72394.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5EN53; -.
DR STRING; 39946.Q5EN53; -.
DR EnsemblPlants; BGIOSGA002459-TA; BGIOSGA002459-PA; BGIOSGA002459.
DR Gramene; BGIOSGA002459-TA; BGIOSGA002459-PA; BGIOSGA002459.
DR HOGENOM; CLU_146278_0_0_1; -.
DR OMA; APPRALC; -.
DR Proteomes; UP000007015; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0042742; P:defense response to bacterium; IEA:EnsemblPlants.
DR GO; GO:0010112; P:regulation of systemic acquired resistance; IEA:InterPro.
DR InterPro; IPR031425; NPR1/NH1-interacting.
DR PANTHER; PTHR33669; PTHR33669; 1.
PE 1: Evidence at protein level;
KW Nucleus; Plant defense; Reference proteome.
FT CHAIN 1..131
FT /note="Protein NEGATIVE REGULATOR OF RESISTANCE"
FT /id="PRO_0000437007"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 51..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 12..15
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000305|PubMed:16115061"
FT MUTAGEN 39
FT /note="E->K: Slightly reduces NPR1/NH1 binding efficiency."
FT /evidence="ECO:0000269|PubMed:16115061"
FT MUTAGEN 40
FT /note="F->G: Slightly reduces NPR1/NH1 binding efficiency."
FT /evidence="ECO:0000269|PubMed:16115061"
FT MUTAGEN 44
FT /note="L->G: Slightly reduces NPR1/NH1 binding efficiency."
FT /evidence="ECO:0000269|PubMed:16115061"
SQ SEQUENCE 131 AA; 14194 MW; 1F7517A739A18277 CRC64;
MDATTTDATT AKRKRPAASD IADDAPTTVD EVSDAEVEEF YAILRRMRDA TRRLGARPPP
PRAPAWRPSF SWEDFADAPP KQAPPPPQQP ADHERVAENA TPPRRPAPGL DLNVEPPSDA
PATPRSARAP A
