ID   NRTD_SYNY3              Reviewed;         266 AA.
AC   P73265;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Nitrate import ATP-binding protein NrtD {ECO:0000305};
DE            EC=7.3.2.4 {ECO:0000250|UniProtKB:P38046};
GN   Name=nrtD; OrderedLocusNames=sll1082;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- FUNCTION: Part of the ABC transporter complex NrtABCD involved in
CC       nitrate uptake. The complex is probably also involved in nitrite
CC       transport. Probably responsible for energy coupling to the transport
CC       system. {ECO:0000250|UniProtKB:P38046}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + nitrate(out) = ADP + H(+) + nitrate(in) +
CC         phosphate; Xref=Rhea:RHEA:13181, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17632, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.3.2.4;
CC         Evidence={ECO:0000250|UniProtKB:P38046};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (NrtC and
CC       NrtD), two transmembrane proteins (NrtB) and a solute-binding protein
CC       (NrtA). {ECO:0000250|UniProtKB:P38046}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000250|UniProtKB:P38046}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:P38046}; Cytoplasmic side
CC       {ECO:0000250|UniProtKB:P38046}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC       Nitrate/nitrite/cyanate uptake transporter (NitT) (TC 3.A.1.16) family.
CC       {ECO:0000305}.
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DR   EMBL; BA000022; BAA17293.1; -; Genomic_DNA.
DR   PIR; S77446; S77446.
DR   AlphaFoldDB; P73265; -.
DR   SMR; P73265; -.
DR   STRING; 1148.1652371; -.
DR   PaxDb; P73265; -.
DR   EnsemblBacteria; BAA17293; BAA17293; BAA17293.
DR   KEGG; syn:sll1082; -.
DR   eggNOG; COG1116; Bacteria.
DR   InParanoid; P73265; -.
DR   OMA; QSIVTFP; -.
DR   PhylomeDB; P73265; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015414; F:ABC-type nitrate transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell inner membrane; Cell membrane; Ion transport; Membrane;
KW   Nitrate assimilation; Nucleotide-binding; Reference proteome; Translocase;
KW   Transport.
FT   CHAIN           1..266
FT                   /note="Nitrate import ATP-binding protein NrtD"
FT                   /id="PRO_0000092649"
FT   DOMAIN          3..234
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         39..46
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   266 AA;  29920 MW;  8FB7A1D7E0042E27 CRC64;
     MHLEITDLNR VFVGKRGSVV ALKNINMHIE TGEFVCAVGA SGSGKSTLLR LIAGLDTPTS
     GTINVDGQRV TGPGADRGMV FQHYSLFPWM TVRQNVEFGL KLQGCSQKER FDTASYYLDV
     VGLINFSEAY PRELSGGMKQ RVAIARSLAC HPKVLLMDEP FGALDIQTKE RMHEYLIDIW
     QRLQCSILMI THDVEEAVFL AQRVYVLSSR PGTIQRELTI NLPGDEETPK NRTYKIKREP
     EFFKYSDEIS SLLRGRETEE TEAIAS