NRX12_ORYSJ
ID NRX12_ORYSJ Reviewed; 581 AA.
AC Q7Y0F2; A0A0P0VZE5; Q0DR93; Q60EC7;
DT 15-JUN-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Probable nucleoredoxin 1-2;
DE Short=OsNrx1-2;
DE EC=1.8.1.8;
GN OrderedLocusNames=Os03g0405900, LOC_Os03g29240;
GN ORFNames=OsJ_11208, OSJNBa0002D18.22, OSJNBb0074M06.3;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RG The rice full-length cDNA consortium;
RT "Oryza sativa full length cDNA.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19825616; DOI=10.1093/mp/ssn076;
RA Chibani K., Wingsle G., Jacquot J.P., Gelhaye E., Rouhier N.;
RT "Comparative genomic study of the thioredoxin family in photosynthetic
RT organisms with emphasis on Populus trichocarpa.";
RL Mol. Plant 2:308-322(2009).
CC -!- FUNCTION: Probable thiol-disulfide oxidoreductase that may participate
CC in various redox reactions.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-dithiol + NAD(+) = [protein]-disulfide + H(+) +
CC NADH; Xref=Rhea:RHEA:18749, Rhea:RHEA-COMP:10593, Rhea:RHEA-
CC COMP:10594, ChEBI:CHEBI:15378, ChEBI:CHEBI:29950, ChEBI:CHEBI:50058,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.8.1.8;
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-dithiol + NADP(+) = [protein]-disulfide + H(+) +
CC NADPH; Xref=Rhea:RHEA:18753, Rhea:RHEA-COMP:10593, Rhea:RHEA-
CC COMP:10594, ChEBI:CHEBI:15378, ChEBI:CHEBI:29950, ChEBI:CHEBI:50058,
CC ChEBI:CHEBI:57783, ChEBI:CHEBI:58349; EC=1.8.1.8;
CC -!- SIMILARITY: Belongs to the nucleoredoxin family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAU89249.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAF12245.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC133932; AAP50932.1; -; Genomic_DNA.
DR EMBL; AC134886; AAU89249.1; ALT_SEQ; Genomic_DNA.
DR EMBL; DP000009; ABF96516.1; -; Genomic_DNA.
DR EMBL; AP008209; BAF12245.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014959; BAS84632.1; -; Genomic_DNA.
DR EMBL; CM000140; EEE59229.1; -; Genomic_DNA.
DR EMBL; AK243686; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015630416.1; XM_015774930.1.
DR AlphaFoldDB; Q7Y0F2; -.
DR SMR; Q7Y0F2; -.
DR STRING; 4530.OS03T0405900-01; -.
DR PaxDb; Q7Y0F2; -.
DR PRIDE; Q7Y0F2; -.
DR EnsemblPlants; Os03t0405900-01; Os03t0405900-01; Os03g0405900.
DR GeneID; 4333077; -.
DR Gramene; Os03t0405900-01; Os03t0405900-01; Os03g0405900.
DR KEGG; osa:4333077; -.
DR eggNOG; KOG2501; Eukaryota.
DR HOGENOM; CLU_019626_1_0_1; -.
DR InParanoid; Q7Y0F2; -.
DR OMA; HNDFEIV; -.
DR OrthoDB; 1350271at2759; -.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000007752; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR Genevisible; Q7Y0F2; OS.
DR GO; GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:InterPro.
DR CDD; cd03009; TryX_like_TryX_NRX; 2.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR004146; DC1.
DR InterPro; IPR012336; Thioredoxin-like_fold.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR017937; Thioredoxin_CS.
DR InterPro; IPR013766; Thioredoxin_domain.
DR InterPro; IPR045870; TryX_NRX_thioredoxin_dom.
DR Pfam; PF03107; C1_2; 1.
DR Pfam; PF13905; Thioredoxin_8; 3.
DR SUPFAM; SSF52833; SSF52833; 3.
DR SUPFAM; SSF57889; SSF57889; 1.
DR PROSITE; PS00194; THIOREDOXIN_1; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 2.
PE 2: Evidence at transcript level;
KW NAD; Oxidoreductase; Reference proteome; Repeat.
FT CHAIN 1..581
FT /note="Probable nucleoredoxin 1-2"
FT /id="PRO_0000394850"
FT DOMAIN 1..165
FT /note="Thioredoxin 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT DOMAIN 178..322
FT /note="Thioredoxin 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT DOMAIN 328..488
FT /note="Thioredoxin 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT CONFLICT 43
FT /note="T -> A (in Ref. 6; AK243686)"
FT /evidence="ECO:0000305"
FT CONFLICT 518
FT /note="R -> H (in Ref. 6; AK243686)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 581 AA; 64422 MW; 35B25A514E484436 CRC64;
MADATHAAAD GGVATILASA DGRDFLLRNS ADKVKISSIK ASTVALYFSA SWCPPCRRFT
PKLIEAYNEL VSQGKSFEVV FVSGDSDQDA FNAYFAKMPW LAVPFSDSEA LAKLNERYKV
MGIPHLVILD AKSGEIYTED GVELVHEYGT EAYPFTTERI NELKEQEKAA KDNQTIHSLF
GTPTRDYLIT NKGDKVPISD LEGKYVGLCF VVNGYGPVVQ FTSVLAKIYE KLKAVGEKFE
VVMVSLDGDE ESFNESFADM PWLAIPQGDK MCEKLARYFE LSGLPMLVLI GPDGKTLNDD
IADIIDEHGP DAWEGFPFSA EKLEILAEKA KAKAESQTLE SLLVTGDLDF VLGKDGAKVP
VSELVGKTVL LYFSAKWCPP CRAFLPKLVN EYNKIKEKHN DFEIVFISSD REQSSYDEFF
SGMPWLALPL GDERKQQLSK IFKITGIPSL VAIGPDGKTV TKDAKTPLVA HGADAFPFTE
EKLQELEKEK EKKINDMAKG WPEKLKHDLH DHELVLTRCT TYGCDGCDEM GDSWSYRCKE
CDFDLHPKCA LEEKGDVEMG EENAEAAPAG YVCEGDVCRK V
