NRX3_ORYSJ
ID NRX3_ORYSJ Reviewed; 471 AA.
AC Q7XPE8; Q0JAA8;
DT 15-JUN-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2004, sequence version 2.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=Probable nucleoredoxin 3;
DE Short=OsNrx3;
DE EC=1.8.1.8;
GN OrderedLocusNames=Os04g0608600, LOC_Os04g51920; ORFNames=OSJNBa0060N03.13;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19825616; DOI=10.1093/mp/ssn076;
RA Chibani K., Wingsle G., Jacquot J.P., Gelhaye E., Rouhier N.;
RT "Comparative genomic study of the thioredoxin family in photosynthetic
RT organisms with emphasis on Populus trichocarpa.";
RL Mol. Plant 2:308-322(2009).
CC -!- FUNCTION: Probable thiol-disulfide oxidoreductase that may participate
CC in various redox reactions.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-dithiol + NAD(+) = [protein]-disulfide + H(+) +
CC NADH; Xref=Rhea:RHEA:18749, Rhea:RHEA-COMP:10593, Rhea:RHEA-
CC COMP:10594, ChEBI:CHEBI:15378, ChEBI:CHEBI:29950, ChEBI:CHEBI:50058,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.8.1.8;
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-dithiol + NADP(+) = [protein]-disulfide + H(+) +
CC NADPH; Xref=Rhea:RHEA:18753, Rhea:RHEA-COMP:10593, Rhea:RHEA-
CC COMP:10594, ChEBI:CHEBI:15378, ChEBI:CHEBI:29950, ChEBI:CHEBI:50058,
CC ChEBI:CHEBI:57783, ChEBI:CHEBI:58349; EC=1.8.1.8;
CC -!- SIMILARITY: Belongs to the nucleoredoxin family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF15729.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL606691; CAE03648.2; -; Genomic_DNA.
DR EMBL; AP008210; BAF15729.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014960; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; Q7XPE8; -.
DR SMR; Q7XPE8; -.
DR STRING; 4530.OS04T0608600-01; -.
DR PaxDb; Q7XPE8; -.
DR PRIDE; Q7XPE8; -.
DR eggNOG; KOG2501; Eukaryota.
DR InParanoid; Q7XPE8; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR GO; GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:InterPro.
DR CDD; cd03009; TryX_like_TryX_NRX; 2.
DR InterPro; IPR012336; Thioredoxin-like_fold.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR InterPro; IPR045870; TryX_NRX_thioredoxin_dom.
DR Pfam; PF13905; Thioredoxin_8; 2.
DR SUPFAM; SSF52833; SSF52833; 2.
DR PROSITE; PS51352; THIOREDOXIN_2; 2.
PE 3: Inferred from homology;
KW NAD; Oxidoreductase; Reference proteome; Repeat.
FT CHAIN 1..471
FT /note="Probable nucleoredoxin 3"
FT /id="PRO_0000394852"
FT DOMAIN 15..173
FT /note="Thioredoxin 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT DOMAIN 179..334
FT /note="Thioredoxin 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
SQ SEQUENCE 471 AA; 53797 MW; 164990C84FFC5FAD CRC64;
MGETAEGVEA GEKYVSIPQL AGVGTLLSNG GKEIPLSSIE GKRICLFFSA HWCRPCRNFT
PKLLQIYRKL RNTCKNMEII FISLDRDEIS FLDYFKGMPW LALPFDTGLR QKLCVQFDIE
HIPALIPLST TLSHGFRVEE DAVKLVEEYG VDAYPFGAKR RSELEGMDDA RRQGGNLLQL
LGCKEREYVI SADGIKTPIS DLNGKTIGLY FGAHWCPPCR AFTKQLREAY DELKALRPGN
FQVIFISMDR NEEEFQASLS AMPWFAIPYS DTTVQELSRI FTIKGIPTLL ILGPDGKVFK
TDGRRIISKY GAMAFPFTES RAYELEEVLK KERDSLPHRV RDHRHEHELE LDMAKAYLST
QLFHQTPSVQ PCRLNLKTLR EEYHLIFTNS NRKTSRPQSS YTRQQRDLNN LYSDPKHLPQ
LHKHFDQSNV ATAENSLRFL NGEPENSDIS SIHVAFADLA GKIRGEDDKR D
