ID   NS12_CVBQ               Reviewed;         109 AA.
AC   Q8V6W3; Q9DR78; Q9QAR2;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   17-APR-2007, sequence version 2.
DT   23-FEB-2022, entry version 39.
DE   RecName: Full=Non-structural protein of 12.7 kDa;
DE            Short=ns12.7;
DE   AltName: Full=12.7 kDa accessory protein;
GN   ORFNames=5a;
OS   Bovine coronavirus (strain Quebec) (BCoV) (BCV).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
OC   Betacoronavirus; Embecovirus.
OX   NCBI_TaxID=11133;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC   STRAIN=Isolate BCQ.1523, Isolate BCQ.2590, Isolate BCQ.3994,
RC   Isolate BCQ.571, and Isolate BCQ.7373;
RX   PubMed=11376845; DOI=10.1016/s0168-1702(01)00243-x;
RA   Gelinas A.-M., Boutin M., Sasseville A.M.-J., Dea S.;
RT   "Bovine coronaviruses associated with enteric and respiratory diseases in
RT   Canadian dairy cattle display different reactivities to anti-HE monoclonal
RT   antibodies and distinct amino acid changes in their HE, S and ns4.9
RT   protein.";
RL   Virus Res. 76:43-57(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC   STRAIN=Isolate Yoo;
RX   PubMed=11774548;
RA   Yoo D., Pei Y.;
RT   "Full-length genomic sequence of bovine coronavirus (31 kb). Completion of
RT   the open reading frame 1a/1b sequences.";
RL   Adv. Exp. Med. Biol. 494:73-76(2001).
CC   -!- SIMILARITY: Belongs to the coronaviruses ns12.7 protein family.
CC       {ECO:0000305}.
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DR   EMBL; AF239312; AAG40608.1; -; Genomic_RNA.
DR   EMBL; AF239313; AAK01074.1; -; Genomic_RNA.
DR   EMBL; AF239314; AAG40598.1; -; Genomic_RNA.
DR   EMBL; AF239315; AAK01078.1; -; Genomic_RNA.
DR   EMBL; AF239316; AAG40604.1; -; Genomic_RNA.
DR   EMBL; AF220295; AAL40403.1; -; Genomic_RNA.
DR   RefSeq; NP_150080.1; NC_003045.1.
DR   GeneID; 1724647; -.
DR   KEGG; vg:1724647; -.
DR   Proteomes; UP000008572; Genome.
DR   InterPro; IPR006841; Corona_NS2.
DR   Pfam; PF04753; Corona_NS12-7; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..109
FT                   /note="Non-structural protein of 12.7 kDa"
FT                   /id="PRO_0000283954"
FT   VARIANT         5
FT                   /note="K -> R (in strain: Isolate Yoo)"
FT   VARIANT         43
FT                   /note="S -> I (in strain: Isolate BCQ.7373)"
FT   VARIANT         45
FT                   /note="A -> V (in strain: Isolate Yoo)"
FT   VARIANT         83..87
FT                   /note="VEEAV -> ARGGC (in strain: Isolate Yoo)"
FT   VARIANT         87..109
FT                   /note="Missing (in strain: Isolate Yoo)"
SQ   SEQUENCE   109 AA;  12778 MW;  166639FCA6E801BC CRC64;
     MDIWKPEIKY LRYTNGFNVS ELEDACFKFN YKFPKVGYCR VPSHAWCRNQ GSFCATLTLY
     GKSKHYDKYF GVITGFTAFA NTVEEAVNKL VFLAVDFITW RRQELNVYG