ID   NS12_CVHN2              Reviewed;         109 AA.
AC   Q14EA9;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   07-OCT-2020, entry version 25.
DE   RecName: Full=Non-structural protein 4;
DE            Short=ns4;
DE   AltName: Full=Accessory protein 4;
DE   AltName: Full=Non-structural protein of 12.5 kDa;
DE            Short=ns12.5;
DE   AltName: Full=Orf4 protein;
GN   ORFNames=4;
OS   Human coronavirus HKU1 (isolate N2) (HCoV-HKU1).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
OC   Betacoronavirus; Embecovirus.
OX   NCBI_TaxID=443240;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=16809319; DOI=10.1128/jvi.00509-06;
RA   Woo P.C.Y., Lau S.K.P., Yip C.C.Y., Huang Y., Tsoi H.-W., Chan K.-H.,
RA   Yuen K.-Y.;
RT   "Comparative analysis of 22 coronavirus HKU1 genomes reveals a novel
RT   genotype and evidence of natural recombination in coronavirus HKU1.";
RL   J. Virol. 80:7136-7145(2006).
CC   -!- MISCELLANEOUS: Isolate N2 belongs to genotype B.
CC   -!- SIMILARITY: Belongs to the coronaviruses ns12.7 protein family.
CC       {ECO:0000305}.
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DR   EMBL; AY884001; AAX76522.1; -; Genomic_RNA.
DR   Proteomes; UP000006551; Genome.
DR   InterPro; IPR006841; Corona_NS2.
DR   Pfam; PF04753; Corona_NS12-7; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..109
FT                   /note="Non-structural protein 4"
FT                   /id="PRO_0000297771"
SQ   SEQUENCE   109 AA;  12567 MW;  AD26A52B63200FB7 CRC64;
     MEVWRPSYKY SLITREFGVT DLEDLCFKYN YCQPCVGYCI VPLNVWCRKF GKFASYFVLR
     SHDTSHKNNF GVITSFTSYG NTVSEAVSKL VESASDFIAW RAEALNKYG