NS12_CVMA5
ID NS12_CVMA5 Reviewed; 112 AA.
AC P0C5A7;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 24-JUL-2007, sequence version 1.
DT 07-OCT-2020, entry version 27.
DE RecName: Full=Non-structural protein of 12.7 kDa;
DE Short=ns12.7;
DE AltName: Full=12.7 kDa accessory protein;
GN ORFNames=5a;
OS Murine coronavirus (strain A59) (MHV-A59) (Murine hepatitis virus).
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
OC Betacoronavirus; Embecovirus.
OX NCBI_TaxID=11142;
OH NCBI_TaxID=10090; Mus musculus (Mouse).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC STRAIN=Isolate C12 mutant;
RX PubMed=9426441; DOI=10.1006/viro.1997.8877;
RA Leparc-Goffart I., Hingley S.T., Chua M.M., Jiang X., Lavi E., Weiss S.R.;
RT "Altered pathogenesis of a mutant of the murine coronavirus MHV-A59 is
RT associated with a Q159L amino acid substitution in the spike protein.";
RL Virology 239:1-10(1997).
CC -!- SIMILARITY: Belongs to the coronaviruses 12.7 kDa protein family.
CC {ECO:0000305}.
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DR EMBL; AF029248; -; NOT_ANNOTATED_CDS; Genomic_RNA.
DR TCDB; 1.A.49.1.2; the human coronavirus ns12,9 viroporin (ns12,9) family.
DR Proteomes; UP000007192; Genome.
DR InterPro; IPR006841; Corona_NS2.
DR Pfam; PF04753; Corona_NS12-7; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..112
FT /note="Non-structural protein of 12.7 kDa"
FT /id="PRO_0000296314"
SQ SEQUENCE 112 AA; 13129 MW; 9D42520A91A9570B CRC64;
MRPTATWIWH VSDAWLRRTR DFGVIRLEDF CFQFNYSQPR VGYCRVPLKA WCSNQGKFAA
QFTLKSCEKP GHEKFITSFT AYGRTVQQAV SKLVEEAVDF ILFRATQLER NV