ID   NS3A_CVPPU              Reviewed;          71 AA.
AC   P09046; Q779N3;
DT   01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1988, sequence version 1.
DT   23-FEB-2022, entry version 56.
DE   RecName: Full=Non-structural protein 3a;
DE            Short=ns3a;
DE   AltName: Full=Accessory protein 3a;
DE   AltName: Full=X2a protein;
GN   ORFNames=3a;
OS   Porcine transmissible gastroenteritis coronavirus (strain Purdue) (TGEV).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
OC   Alphacoronavirus; Tegacovirus.
OX   NCBI_TaxID=11151;
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2825819; DOI=10.1016/0300-9084(87)90178-7;
RA   Rasschaert D., Gelfi J., Laude H.;
RT   "Enteric coronavirus TGEV: partial sequence of the genomic RNA, its
RT   organization and expression.";
RL   Biochimie 69:591-600(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2548340; DOI=10.1007/bf00125345;
RA   Kapke P.A., Tung F.Y., Brian D.A.;
RT   "Nucleotide sequence between the peplomer and matrix protein genes of the
RT   porcine transmissible gastroenteritis coronavirus identifies three large
RT   open reading frames.";
RL   Virus Genes 2:293-294(1989).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC   STRAIN=Isolate PUR46-MAD;
RX   PubMed=10805807; DOI=10.1073/pnas.97.10.5516;
RA   Almazan F., Gonzalez J.M., Penzes Z., Izeta A., Calvo E., Plana-Duran J.,
RA   Enjuanes L.;
RT   "Engineering the largest RNA virus genome as an infectious bacterial
RT   artificial chromosome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:5516-5521(2000).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC   STRAIN=Isolate SC-Y;
RA   Song Z.H., Guo W.Z., Yin H.P., Zeng Z.Y., Ou Y., Han G.Q., Sun Z.Y.;
RT   "Cloning and Seqence Analysis of Genome of Transmissible gastroenteritis
RT   virus SC-Y strain.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; X06371; CAA29670.1; -; Genomic_RNA.
DR   EMBL; X12800; CAA31286.1; -; Genomic_RNA.
DR   EMBL; AJ271965; CAB91146.1; -; Genomic_RNA.
DR   EMBL; DQ443743; ABD97836.1; -; Genomic_RNA.
DR   PIR; S01739; S01739.
DR   Proteomes; UP000001440; Genome.
DR   Proteomes; UP000158504; Genome.
DR   InterPro; IPR006784; Coronavirus_Orf3.
DR   Pfam; PF04694; Corona_3; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..71
FT                   /note="Non-structural protein 3a"
FT                   /id="PRO_0000106102"
SQ   SEQUENCE   71 AA;  7710 MW;  433A511590A3A83A CRC64;
     MDIVKSIYTS VDAVLDELDC AYFAVTLKVE FKTGKLLVCI GFGDTLLAAK DKAYAKLGLS
     IIEEVNSHIV V