ID   NS4_CVMJH               Reviewed;         139 AA.
AC   Q66181;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Non-structural protein 4;
DE            Short=ns4;
DE   AltName: Full=Accessory protein 4;
GN   ORFNames=4;
OS   Murine coronavirus (strain JHM) (MHV-JHM) (Murine hepatitis virus).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
OC   Betacoronavirus; Embecovirus.
OX   NCBI_TaxID=11144;
OH   NCBI_TaxID=10090; Mus musculus (Mouse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=3973564; DOI=10.1099/0022-1317-66-3-593;
RA   Skinner M.A., Siddell S.G.;
RT   "Coding sequence of coronavirus MHV-JHM mRNA 4.";
RL   J. Gen. Virol. 66:593-596(1985).
CC   -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the coronaviruses ns4/ns4.8 protein family.
CC       {ECO:0000305}.
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DR   EMBL; X04998; CAA28657.1; -; Genomic_RNA.
DR   RefSeq; YP_209234.1; AC_000192.1.
DR   SMR; Q66181; -.
DR   KEGG; vg:3283256; -.
DR   Proteomes; UP000007193; Genome.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR005603; Corona_NS4.
DR   Pfam; PF03905; Corona_NS4; 1.
PE   3: Inferred from homology;
KW   Host membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..139
FT                   /note="Non-structural protein 4"
FT                   /id="PRO_0000283965"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   139 AA;  15203 MW;  5D18886D190B3F71 CRC64;
     MALIGPKTTI AAVFIGPFLV ACMLGIGLVY LLQLQVQIFH VKDTIRVTGK PATVSYTTST
     PVTPVATTLD GTTYTLIRPT SSYTRVYLGS SRGFDTSTFG PKTLDYITSS KPHLNSGRPY
     TLRHLPKYMT PPATWRFGL