ID   NS7B_BCHK3              Reviewed;          44 AA.
AC   Q3LZX6;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 50.
DE   RecName: Full=Non-structural protein 7b;
DE            Short=ns7b;
DE   AltName: Full=Accessory protein 7b;
GN   ORFNames=7b;
OS   Bat coronavirus HKU3 (BtCoV) (SARS-like coronavirus HKU3).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
OC   Betacoronavirus; Sarbecovirus.
OX   NCBI_TaxID=442736;
OH   NCBI_TaxID=89399; Rhinolophus sinicus (Chinese rufous horseshoe bat).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC   STRAIN=Isolate HKU3-1;
RX   PubMed=16169905; DOI=10.1073/pnas.0506735102;
RA   Lau S.K.P., Woo P.C.Y., Li K.S.M., Huang Y., Tsoi H.-W., Wong B.H.L.,
RA   Wong S.S.Y., Leung S.-Y., Chan K.-H., Yuen K.-Y.;
RT   "Severe acute respiratory syndrome coronavirus-like virus in Chinese
RT   horseshoe bats.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:14040-14045(2005).
CC   -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- MISCELLANEOUS: Bat coronavirus HKU3 is highly similar to SARS-CoV
CC       (SARS-like).
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DR   EMBL; DQ022305; AAY88872.1; -; Genomic_RNA.
DR   SMR; Q3LZX6; -.
DR   TCDB; 1.A.127.1.3; the sars-cov-2 orf7b viroporin (orf7b viroporin) family.
DR   Proteomes; UP000007450; Genome.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   CDD; cd21635; ORF7b_SARS-CoV-like; 1.
DR   InterPro; IPR021532; NS7B_bCoV.
DR   InterPro; IPR044394; ORF7b_SARS-CoV-like.
DR   Pfam; PF11395; bCoV_NS7B; 1.
PE   4: Predicted;
KW   Host membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..44
FT                   /note="Non-structural protein 7b"
FT                   /id="PRO_0000291332"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   44 AA;  5315 MW;  3BD6549F5311E048 CRC64;
     MNELTLIDFY LCFLAFLLFL VLIMLLIFWF SLEIQDIEEP CNKV