NS7_CVCAI
ID NS7_CVCAI Reviewed; 101 AA.
AC P36301;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 23-FEB-2022, entry version 61.
DE RecName: Full=Non-structural protein 7a;
DE Short=ns7a;
DE AltName: Full=11 kDa protein;
DE AltName: Full=Accessory protein 7a;
DE AltName: Full=X3 protein;
DE Flags: Precursor;
GN ORFNames=7a;
OS Canine coronavirus (strain Insavc-1) (CCoV) (Canine enteric coronavirus).
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
OC Alphacoronavirus; Tegacovirus.
OX NCBI_TaxID=36391;
OH NCBI_TaxID=9615; Canis lupus familiaris (Dog) (Canis familiaris).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=1431811; DOI=10.1099/0022-1317-73-11-2849;
RA Horsburgh B.C., Brierley I., Brown T.D.K.;
RT "Analysis of a 9.6 kb sequence from the 3' end of canine coronavirus
RT genomic RNA.";
RL J. Gen. Virol. 73:2849-2862(1992).
CC -!- FUNCTION: May function in the formation of membrane-bound replication
CC complexes or in the assembly of the virus.
CC -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the coronaviruses ns7/ns7a protein family.
CC {ECO:0000305}.
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DR EMBL; D13096; BAA02415.1; ALT_SEQ; Genomic_RNA.
DR PIR; JQ1726; JQ1726.
DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR003449; Corona_7.
DR Pfam; PF02398; Corona_7; 1.
PE 3: Inferred from homology;
KW Host membrane; Membrane; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..101
FT /note="Non-structural protein 7a"
FT /id="PRO_0000106095"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 101 AA; 11547 MW; 2F24681194DB9BB8 CRC64;
MLVFLHAVFI TVLILLLIGR LQLLERLLLN HSLNLKTVNN VLGVTHTGLK VNCLQLLKPD
CLDFNILHRS LAETRLLKVV LRVIFLVLLG FCCYRLLVTL F