NS7_CVCAK
ID NS7_CVCAK Reviewed; 101 AA.
AC Q04703;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1994, sequence version 1.
DT 23-FEB-2022, entry version 64.
DE RecName: Full=Non-structural protein 7a;
DE Short=ns7a;
DE AltName: Full=11 kDa protein;
DE AltName: Full=Accessory protein 7a;
DE AltName: Full=X3 protein;
DE Flags: Precursor;
GN ORFNames=7a;
OS Canine coronavirus (strain K378) (CCoV) (Canine enteric coronavirus).
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
OC Alphacoronavirus; Tegacovirus.
OX NCBI_TaxID=33732;
OH NCBI_TaxID=9615; Canis lupus familiaris (Dog) (Canis familiaris).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=1329312; DOI=10.1016/0042-6822(92)90174-n;
RA Vennema H., Rossen J.W.A., Wesseling J., Horzinek M.C., Rottier P.J.M.;
RT "Genomic organization and expression of the 3' end of the canine and feline
RT enteric coronaviruses.";
RL Virology 191:134-140(1992).
CC -!- FUNCTION: May function in the formation of membrane-bound replication
CC complexes or in the assembly of the virus.
CC -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the coronaviruses ns7/ns7a protein family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X66717; CAA47247.1; -; Genomic_RNA.
DR PIR; B44056; B44056.
DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR003449; Corona_7.
DR Pfam; PF02398; Corona_7; 1.
PE 3: Inferred from homology;
KW Host membrane; Membrane; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..101
FT /note="Non-structural protein 7a"
FT /id="PRO_0000106094"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 101 AA; 11491 MW; 1AB4641D94DB9BB1 CRC64;
MLVFLHAVFI TVLILLLIGR LQLLERLLLN HSLNLKTVNN VLGVTDTGLK VNCLQLLKPD
CLDFNILHRS LAETRLLKVV LRVIFLVLLG FCCYRLLVTL I