ID   NS7_CVPR8               Reviewed;          78 AA.
AC   P69612; P24416; P33466;
DT   29-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   29-MAR-2005, sequence version 1.
DT   02-JUN-2021, entry version 37.
DE   RecName: Full=Non-structural protein 7;
DE            Short=ns7;
DE   AltName: Full=9 kDa hydrophobic protein;
DE            Short=HP;
DE   AltName: Full=Accessory protein 7;
DE   AltName: Full=X3 protein;
DE   Flags: Precursor;
GN   ORFNames=7;
OS   Porcine respiratory coronavirus (strain 86/137004 / isolate British)
OS   (PRCoV) (PRCV).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
OC   Alphacoronavirus; Tegacovirus.
OX   NCBI_TaxID=33736;
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1662846; DOI=10.1016/0168-1702(91)90032-q;
RA   Britton P., Mawditt K.L., Page K.W.;
RT   "The cloning and sequencing of the virion protein genes from a British
RT   isolate of porcine respiratory coronavirus: comparison with transmissible
RT   gastroenteritis virus genes.";
RL   Virus Res. 21:181-198(1991).
CC   -!- FUNCTION: May function in the formation of membrane-bound replication
CC       complexes or in the assembly of the virus.
CC   -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the coronaviruses ns7/ns7a protein family.
CC       {ECO:0000305}.
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DR   EMBL; X60056; CAA42658.1; -; Genomic_RNA.
DR   PIR; S24283; S24283.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR003449; Corona_7.
DR   Pfam; PF02398; Corona_7; 2.
PE   3: Inferred from homology;
KW   Host membrane; Membrane; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..78
FT                   /note="Non-structural protein 7"
FT                   /id="PRO_0000106100"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   78 AA;  9058 MW;  7C7B067665646B98 CRC64;
     MLVLLQAVCI TVLTLLLIGR LQLLERLLLN HSFNLKTVDD FNILYRSLAE TRLLKVVLRL
     IFLVLLGFCC YRLLVILM