ID   NS7_FIPV                Reviewed;         101 AA.
AC   P19742; Q52PB0;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   02-JUN-2021, entry version 65.
DE   RecName: Full=Non-structural protein 7a;
DE            Short=ns7a;
DE   AltName: Full=11 kDa protein;
DE   AltName: Full=Accessory protein 7a;
DE   Flags: Precursor;
GN   ORFNames=7a;
OS   Feline coronavirus (strain FIPV WSU-79/1146) (FCoV).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
OC   Alphacoronavirus; Tegacovirus.
OX   NCBI_TaxID=33734;
OH   NCBI_TaxID=9681; Felidae (cat family).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=3201747; DOI=10.1016/s0042-6822(88)90097-9;
RA   de Groot R.J., Andeweg A.C., Horzinek M.C., Spaan W.J.M.;
RT   "Sequence analysis of the 3'-end of the feline coronavirus FIPV 79-1146
RT   genome: comparison with the genome of porcine coronavirus TGEV reveals
RT   large insertions.";
RL   Virology 167:370-376(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=16033972; DOI=10.1099/vir.0.80985-0;
RA   Dye C., Siddell S.G.;
RT   "Genomic RNA sequence of Feline coronavirus strain FIPV WSU-79/1146.";
RL   J. Gen. Virol. 86:2249-2253(2005).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RA   Haijema B.J., de Groot-Mijnes J.D.F., Vennema H., Raamsman M.J.,
RA   Rottier P.J.M., de Groot R.J.;
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May function in the formation of membrane-bound replication
CC       complexes or in the assembly of the virus.
CC   -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the coronaviruses ns7/ns7a protein family.
CC       {ECO:0000305}.
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DR   EMBL; M23694; AAA43063.1; -; mRNA.
DR   EMBL; DQ010921; -; NOT_ANNOTATED_CDS; Genomic_RNA.
DR   EMBL; AY994055; AAY16381.1; -; Genomic_RNA.
DR   PIR; A31825; WMIHFI.
DR   RefSeq; YP_004070200.1; NC_002306.3.
DR   SMR; P19742; -.
DR   GeneID; 10040187; -.
DR   KEGG; vg:10040187; -.
DR   Proteomes; UP000000835; Genome.
DR   Proteomes; UP000140386; Genome.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR003449; Corona_7.
DR   Pfam; PF02398; Corona_7; 1.
PE   3: Inferred from homology;
KW   Host membrane; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..43
FT                   /evidence="ECO:0000255"
FT   CHAIN           44..101
FT                   /note="Non-structural protein 7a"
FT                   /id="PRO_0000106096"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   VARIANT         32
FT                   /note="L -> M"
SQ   SEQUENCE   101 AA;  11232 MW;  E901E4E2E9C7DC2E CRC64;
     MLVFVHAVLV TALILLLIGR IQLLERLLLS HLLNLTTVSN VLGVPDSSLR VNCLQLLKPD
     CLDFNILHKV LAETRLLVVV LRVIFLVLLG FSCYTLLGAL F