ID   NSA1_DEBHA              Reviewed;         430 AA.
AC   Q6BUJ2;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Ribosome biogenesis protein NSA1;
GN   Name=NSA1; OrderedLocusNames=DEHA2C10186g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the pre-66S ribosomal particle. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NSA1 family. {ECO:0000305}.
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DR   EMBL; CR382135; CAG86198.1; -; Genomic_DNA.
DR   RefSeq; XP_458127.1; XM_458127.1.
DR   AlphaFoldDB; Q6BUJ2; -.
DR   SMR; Q6BUJ2; -.
DR   STRING; 4959.XP_458127.1; -.
DR   PRIDE; Q6BUJ2; -.
DR   EnsemblFungi; CAG86198; CAG86198; DEHA2C10186g.
DR   GeneID; 2900161; -.
DR   KEGG; dha:DEHA2C10186g; -.
DR   VEuPathDB; FungiDB:DEHA2C10186g; -.
DR   eggNOG; KOG3881; Eukaryota.
DR   HOGENOM; CLU_033769_4_0_1; -.
DR   InParanoid; Q6BUJ2; -.
DR   OMA; IWEAKNV; -.
DR   OrthoDB; 1439033at2759; -.
DR   Proteomes; UP000000599; Chromosome C.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR037379; WDR74/Nsa1.
DR   PANTHER; PTHR16038; PTHR16038; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..430
FT                   /note="Ribosome biogenesis protein NSA1"
FT                   /id="PRO_0000320398"
FT   REGION          372..430
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        381..402
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   430 AA;  48525 MW;  D7534C4E2F616D19 CRC64;
     MKILVTSDDT GAVKEVVCSR GTDTSKQDAK QPKSIKNICS EPGASVRTRV LHMVNFKSTF
     LVASRLGGSV TIYDLNHEEY ELVHTYQLAI SNEDKPISLI ELEEFDVVVV AFESGKVFVI
     NLNNGKFDLD PIEIQLPGKK GISAFINNPH EAGVFACGGK ENDARIIRLF EGEITKDVFE
     AENKQEFFQP DVIFTARNVK NDHLDLRPPI WISSILFFEE KPKDGYKFLT STRYGQVRIY
     DTTHGKRPIQ DYKVCEKPIV TLNFADSEEE VIVSDTHNLV AKYSLAQIDS KAFKTHSASA
     GEITKPVSKL LGKFSAGGNT GAIVGVNIFD DEIISTGGLD RYLRTYDISS REILAKVYLG
     VQISDVLMLD SEDEEEEEPE SEMGDKRKKN IEKRRRKALE AEENESDEEE LWNQLEENNK
     TKIEKKKRRI