ID   NSA1_PICST              Reviewed;         430 AA.
AC   A3LVX0;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 2.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Ribosome biogenesis protein NSA1;
GN   Name=NSA1; ORFNames=PICST_36366;
OS   Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS   Y-11545) (Yeast) (Pichia stipitis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX   NCBI_TaxID=322104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX   PubMed=17334359; DOI=10.1038/nbt1290;
RA   Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA   Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA   Passoth V., Richardson P.M.;
RT   "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT   yeast Pichia stipitis.";
RL   Nat. Biotechnol. 25:319-326(2007).
CC   -!- FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the pre-66S ribosomal particle. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NSA1 family. {ECO:0000305}.
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DR   EMBL; CP000499; ABN67189.2; -; Genomic_DNA.
DR   RefSeq; XP_001385218.2; XM_001385181.1.
DR   AlphaFoldDB; A3LVX0; -.
DR   SMR; A3LVX0; -.
DR   STRING; 4924.XP_001385218.2; -.
DR   PRIDE; A3LVX0; -.
DR   EnsemblFungi; ABN67189; ABN67189; PICST_36366.
DR   GeneID; 4839533; -.
DR   KEGG; pic:PICST_36366; -.
DR   eggNOG; KOG3881; Eukaryota.
DR   HOGENOM; CLU_033769_4_0_1; -.
DR   InParanoid; A3LVX0; -.
DR   OMA; IWEAKNV; -.
DR   OrthoDB; 1439033at2759; -.
DR   Proteomes; UP000002258; Chromosome 5.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR037379; WDR74/Nsa1.
DR   PANTHER; PTHR16038; PTHR16038; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..430
FT                   /note="Ribosome biogenesis protein NSA1"
FT                   /id="PRO_0000320402"
SQ   SEQUENCE   430 AA;  48859 MW;  10CED63F8DC27421 CRC64;
     MKFLVSSDDT GVVKEVICNR GTDTSKQDAT QPISVKNFCT EPNCSRKNRI IHMINYQEKY
     LVAIRIGGEL SVYEIADDEY EIEDEYKYNL LHNYKLEVSS SDKPISLFTV DILEAVAVAF
     SSGKVFFVNF NDDKFDKEPV LVQLPGGKEI AEFSKNPSVE GIFGYGGEEN DVRIVKLYES
     DITSEIFDTE NVENNFKSEV VFTAKNVKND HLDLRVPVWI TKIRFFTEQP EKGYKFITAT
     HYGQIRVYDT NHGRRPVRDF TVCQKPILTL TFANEEESEV IISDSHNLIA KHSLIQVDDK
     ASKTHSASAG DIIKPVAKLL GRFVDQFGAT YGVEVGEGLL VTGGLDRYLR VFDLASREIV
     AKVYVGVEVS SVVVLDYEEE ESQEEIVGDV ELLKKSEKRK RTLPVVEREE SDEEDLWNQL
     EEKDIKRKKS