ID   NSA1_VANPO              Reviewed;         445 AA.
AC   A7TJL1;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Ribosome biogenesis protein NSA1;
GN   Name=NSA1; ORFNames=Kpol_534p34;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the pre-66S ribosomal particle. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NSA1 family. {ECO:0000305}.
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DR   EMBL; DS480402; EDO17554.1; -; Genomic_DNA.
DR   RefSeq; XP_001645412.1; XM_001645362.1.
DR   AlphaFoldDB; A7TJL1; -.
DR   SMR; A7TJL1; -.
DR   STRING; 436907.A7TJL1; -.
DR   EnsemblFungi; EDO17554; EDO17554; Kpol_534p34.
DR   GeneID; 5545777; -.
DR   KEGG; vpo:Kpol_534p34; -.
DR   eggNOG; KOG3881; Eukaryota.
DR   HOGENOM; CLU_033769_4_0_1; -.
DR   InParanoid; A7TJL1; -.
DR   OMA; IWEAKNV; -.
DR   OrthoDB; 1439033at2759; -.
DR   PhylomeDB; A7TJL1; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR037379; WDR74/Nsa1.
DR   PANTHER; PTHR16038; PTHR16038; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..445
FT                   /note="Ribosome biogenesis protein NSA1"
FT                   /id="PRO_0000320404"
SQ   SEQUENCE   445 AA;  51175 MW;  1955408DF0B10E05 CRC64;
     MRVLVSCTDG GSLKEVIFNS GTDTSVQTAL QPLHVETHLE QGLNNYINKI SQLSNGEFLI
     ARSNGVVELV KATLLPKEYT EEPPEGKQFP SFDVNKFEVV DTLAGLLDNK RLEPLYQKSK
     KRTKLIDEFV TVTLLNEKLN IYILASKSGL IHIIKHNSKK SKLEKINSFE VKAPLDFAQL
     YDLEGKMDKY ILGYGGEENL VKLIEINKNF TDLKQIWEAK NVKNDRLDMK VPIWPVSLKF
     LEPYKGEKLE KDKINYQFTT VSRYSHLGKY RTQHGRKPLE YKDLLPNREP LTQLEVISEK
     VTPIGNAQTS EFSDITFITT DTKKDVLKFN HDGRLLLKYG KGDILGSPTF ITISKGKYLL
     QGGLDRYLRV FDINTNERIA KIYVGAKINY ITLLDDDEIE LPEVAKEKEK MKEKSKKREL
     EFEEDNDDQL WNDLDSIKHH KKSKI