ID   NSA1_YARLI              Reviewed;         410 AA.
AC   Q6CEC9;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Ribosome biogenesis protein NSA1;
GN   Name=NSA1; OrderedLocusNames=YALI0B16654g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the pre-66S ribosomal particle. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NSA1 family. {ECO:0000305}.
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DR   EMBL; CR382128; CAG83236.1; -; Genomic_DNA.
DR   RefSeq; XP_500983.1; XM_500983.1.
DR   AlphaFoldDB; Q6CEC9; -.
DR   SMR; Q6CEC9; -.
DR   STRING; 4952.CAG83236; -.
DR   EnsemblFungi; CAG83236; CAG83236; YALI0_B16654g.
DR   GeneID; 2907266; -.
DR   KEGG; yli:YALI0B16654g; -.
DR   VEuPathDB; FungiDB:YALI0_B16654g; -.
DR   HOGENOM; CLU_033769_4_0_1; -.
DR   InParanoid; Q6CEC9; -.
DR   OMA; IWEAKNV; -.
DR   Proteomes; UP000001300; Chromosome B.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR037379; WDR74/Nsa1.
DR   PANTHER; PTHR16038; PTHR16038; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..410
FT                   /note="Ribosome biogenesis protein NSA1"
FT                   /id="PRO_0000320405"
FT   REGION          366..385
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          390..410
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   410 AA;  45636 MW;  1904E283FD53CAAB CRC64;
     MKIFLAAEDT GAIKEVVFDE GMDTSVQDGP QPLITSFAAL GKLKHIQKLA LVTTSKGTKY
     IAAARKNGTI EVYPYLLTEE STPIFVYSAE GAEKCPWIGL TQYDDNTVVA GLEDGRLFFL
     DVSKVTIESD KPYDAPTASV KGPLACFALD RELYPGKIAV GGKERDLEVF GWAVKGDEVT
     VRSEFQARNV KSNEIDMRVP VWISGILFQA SDKDGFRVIT ATRHGQIRVY ETWHGKRPKW
     DFKVTKDPLR TLAPGMDASN VVSSDAHSST FKFNFADNEK IVLKNKDNNQ NKEHNRKSPC
     VVEKFPGSLG AVLHLVTTDN GLLATVGLDR YLRIFDLETT ECTAKMFVGT QVSSLLFVDT
     ERKTAQEKHV EETAEKEDDE LWNDLDKVEK KSNKRRVAGN DEGKKKLKSA