ID   NSA1_YEAS7              Reviewed;         463 AA.
AC   A6ZU71;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=Ribosome biogenesis protein NSA1;
DE   AltName: Full=NOP7-associated protein 1;
GN   Name=NSA1; ORFNames=SCY_1954;
OS   Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=307796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJM789;
RX   PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA   Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA   Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA   Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA   Steinmetz L.M.;
RT   "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT   strain YJM789.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC   -!- FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the pre-66S ribosomal particle. Interacts with
CC       NOP7, RRP1 and RRP5 (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NSA1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAFW02000099; EDN62009.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6ZU71; -.
DR   SMR; A6ZU71; -.
DR   EnsemblFungi; EDN62009; EDN62009; SCY_1954.
DR   HOGENOM; CLU_033769_4_0_1; -.
DR   Proteomes; UP000007060; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR037379; WDR74/Nsa1.
DR   PANTHER; PTHR16038; PTHR16038; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Nucleus; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..463
FT                   /note="Ribosome biogenesis protein NSA1"
FT                   /id="PRO_0000320406"
SQ   SEQUENCE   463 AA;  51933 MW;  2C16C2B378594964 CRC64;
     MRLLVSCVDS GSIKEVLCNI GTDTSVQSAL QPFHVAPHLA EGLKAYVDRM WVISEDEAIL
     ARNSGVVELV KISKHLKENE ALQVDPKGES KNEKSLSDDL PKFDISEFEI TSSVSDLFDD
     AKLESLSSKS VKRTKLVDGF VTLCPIKKDS SNNTFVAATK SGLLHIIKKG EDKKLIKLAS
     LGLKAPVEFL QLYDLEDTDT DKYIFAYGGE ENLIKLVEID SSFQSLKQIW EAKNVKNDRL
     DMRVPVWPMA LRFLEPSPGK TEKGKLNYQF AAITRWSHLT KYSTQHGRKP FAQIDLLPNR
     EPLSQMEVFD AKGENVVSLL GNFQSETCND LNVISTDYKK NVFKFDGNGR MLGKVGRDDI
     TGSSTYIHVH DGKYLLQGGL DRYVRIFDIK TNKMLVKVYV GSRINFIVML DDVEIEMPLS
     PSAKAAKEKQ KRKVTELEED ADELWNKLEG KVAASKASKK SKI