ID   AROK_METJA              Reviewed;         282 AA.
AC   Q58835;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 126.
DE   RecName: Full=Shikimate kinase;
DE            Short=SK;
DE            EC=2.7.1.71;
GN   Name=aroK; OrderedLocusNames=MJ1440;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
RN   [2]
RP   CATALYTIC ACTIVITY, PATHWAY, AND SUBCELLULAR LOCATION.
RX   PubMed=11114929; DOI=10.1128/jb.183.1.292-300.2001;
RA   Daugherty M., Vonstein V., Overbeek R., Osterman A.;
RT   "Archaeal shikimate kinase, a new member of the GHMP-kinase family.";
RL   J. Bacteriol. 183:292-300(2001).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + shikimate = 3-phosphoshikimate + ADP + H(+);
CC         Xref=Rhea:RHEA:13121, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:36208, ChEBI:CHEBI:145989, ChEBI:CHEBI:456216;
CC         EC=2.7.1.71; Evidence={ECO:0000269|PubMed:11114929};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis;
CC       chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step
CC       5/7. {ECO:0000269|PubMed:11114929}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305|PubMed:11114929}.
CC   -!- SIMILARITY: Belongs to the GHMP kinase family. Archaeal shikimate
CC       kinase subfamily. {ECO:0000305}.
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DR   EMBL; L77117; AAB99451.1; -; Genomic_DNA.
DR   PIR; G64479; G64479.
DR   RefSeq; WP_010870958.1; NC_000909.1.
DR   AlphaFoldDB; Q58835; -.
DR   SMR; Q58835; -.
DR   STRING; 243232.MJ_1440; -.
DR   EnsemblBacteria; AAB99451; AAB99451; MJ_1440.
DR   GeneID; 1452344; -.
DR   KEGG; mja:MJ_1440; -.
DR   eggNOG; arCOG01025; Archaea.
DR   HOGENOM; CLU_073768_0_0_2; -.
DR   InParanoid; Q58835; -.
DR   OMA; WDVLVWT; -.
DR   OrthoDB; 98200at2157; -.
DR   PhylomeDB; Q58835; -.
DR   BioCyc; MetaCyc:MON-18801; -.
DR   SABIO-RK; Q58835; -.
DR   UniPathway; UPA00053; UER00088.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004765; F:shikimate kinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.230.10; -; 1.
DR   Gene3D; 3.30.70.890; -; 1.
DR   HAMAP; MF_00370; Shik_kinase_arch; 1.
DR   InterPro; IPR013750; GHMP_kinase_C_dom.
DR   InterPro; IPR036554; GHMP_kinase_C_sf.
DR   InterPro; IPR006204; GHMP_kinase_N_dom.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR014721; Ribosomal_S5_D2-typ_fold_subgr.
DR   InterPro; IPR010189; SK_arc.
DR   PANTHER; PTHR20861:SF3; PTHR20861:SF3; 1.
DR   Pfam; PF08544; GHMP_kinases_C; 1.
DR   Pfam; PF00288; GHMP_kinases_N; 1.
DR   PIRSF; PIRSF005758; Shikimt_kin_arch; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55060; SSF55060; 1.
DR   TIGRFAMs; TIGR01920; Shik_kin_archae; 1.
PE   1: Evidence at protein level;
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis; ATP-binding;
KW   Cytoplasm; Kinase; Nucleotide-binding; Reference proteome; Transferase.
FT   CHAIN           1..282
FT                   /note="Shikimate kinase"
FT                   /id="PRO_0000141574"
FT   BINDING         86..96
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   282 AA;  30598 MW;  20EDBD4B736AE011 CRC64;
     MEGKAYALAS GTIINAIATG KGSAFGLDLK VYAKVKLIDD GKNKIEGKVL DNPNIKPNLI
     VRCVKNTLDY FGLNYSAYVE TKTEIPIKSG LSSSSATSNA VVLATFDALG EKIDDELILN
     LGIKSSFDEK LTVTGAYDDA TASYYGGITI TDNIERKILK RDKMRDDLNV LILIPNLEKN
     VDVNRMKLIK DYVEIAFNEA INGNYFKALF LNGILYASAL NFPTNIAIDA LDAGAITAGL
     SGTGPSYIAM VEDENVEKVK EKLNRYGKVI LTKPNNDGAS IY