ID   NSP12_RDVA              Reviewed;         312 AA.
AC   Q05054;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   02-JUN-2021, entry version 44.
DE   RecName: Full=Non-structural protein 12A;
DE            Short=Pns12A;
OS   Rice dwarf virus (isolate Akita) (RDV).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Phytoreovirus.
OX   NCBI_TaxID=142803;
OH   NCBI_TaxID=114194; Alopecurus aequalis.
OH   NCBI_TaxID=90397; Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli).
OH   NCBI_TaxID=94400; Nephotettix cincticeps (Green rice leafhopper) (Selenocephalus cincticeps).
OH   NCBI_TaxID=4530; Oryza sativa (Rice).
OH   NCBI_TaxID=147271; Paspalum.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1448932; DOI=10.1016/0042-6822(92)90279-x;
RA   Suzuki N., Sugawara M., Kusano T.;
RT   "Rice dwarf phytoreovirus segment S12 transcript is tricistronic in
RT   vitro.";
RL   Virology 191:992-995(1992).
CC   -!- FUNCTION: Constituent of viral factories. Binds to ssRNA and dsRNA (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000250}. Note=Constituent of
CC       spherical cytoplasmic structures, called virus factories, that appear
CC       early after infection and are the site of viral replication and
CC       packaging. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the phytoreovirus non-structural protein Pns12A
CC       family. {ECO:0000305}.
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DR   EMBL; D90200; BAA14223.1; -; Genomic_RNA.
DR   PIR; A44219; A44219.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Host cytoplasm.
FT   CHAIN           1..312
FT                   /note="Non-structural protein 12A"
FT                   /id="PRO_0000222802"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          62..99
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          111..161
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..23
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        74..99
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        113..155
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   312 AA;  33920 MW;  5891726389A42FCF CRC64;
     MFKSGSGSLK RSGSISSVKS FSGDSEKGLP PISRGSVSIA SQNSEPLIVP ASSSSFAATS
     DFVPEKTKSE GNLKDKSSVI TGNFGSSGPI NAHTNQNADG DRLVENLLLK ESSKGRGSGT
     SDARHTATDS RLSQEVKQSF SEENAGGNDL NTGRGSHGTG DGVEQHYKFD CEEGMSAYHK
     RVVDTFFKYF EYSAEDGHST LYSDVMFLSG HGDLGLLVMS RYQELMTLRV RSAIYGIFCY
     LQALTAYLTY FDAKVGQAIM LDEELEKYEI RLDVAQDDDP IVFQITTGVF TSGVAHDLRK
     LTQILEAFSL ER