ID   NSP12_RDVF              Reviewed;         312 AA.
AC   Q85443;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   02-JUN-2021, entry version 45.
DE   RecName: Full=Non-structural protein 12A;
DE            Short=Pns12A;
OS   Rice dwarf virus (isolate Fujian) (RDV).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Phytoreovirus.
OX   NCBI_TaxID=142804;
OH   NCBI_TaxID=114194; Alopecurus aequalis.
OH   NCBI_TaxID=90397; Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli).
OH   NCBI_TaxID=94400; Nephotettix cincticeps (Green rice leafhopper) (Selenocephalus cincticeps).
OH   NCBI_TaxID=4530; Oryza sativa (Rice).
OH   NCBI_TaxID=147271; Paspalum.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Li Y., Xue Z., Liu Y., Quan S., Pan N., Chen Z.;
RT   "cDNA synthesis, molecular cloning and sequence analysis of rice dwarf
RT   virus segment S12.";
RL   Ping Tu Hsueh Pao 10:339-345(1994).
RN   [2]
RP   FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=16432031; DOI=10.1099/vir.0.81425-0;
RA   Wei T., Shimizu T., Hagiwara K., Kikuchi A., Moriyasu Y., Suzuki N.,
RA   Chen H., Omura T.;
RT   "Pns12 protein of Rice dwarf virus is essential for formation of viroplasms
RT   and nucleation of viral-assembly complexes.";
RL   J. Gen. Virol. 87:429-438(2006).
CC   -!- FUNCTION: Constituent of viral factories. {ECO:0000250,
CC       ECO:0000269|PubMed:16432031}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000269|PubMed:16432031}.
CC       Note=Constituent of spherical cytoplasmic structures, called virus
CC       factories, that appear early after infection and are the site of viral
CC       replication and packaging.
CC   -!- SIMILARITY: Belongs to the phytoreovirus non-structural protein Pns12A
CC       family. {ECO:0000305}.
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DR   EMBL; U36569; AAA88768.1; -; mRNA.
DR   RefSeq; NP_620538.1; NC_003768.1.
DR   GeneID; 956503; -.
DR   KEGG; vg:956503; -.
DR   Proteomes; UP000002239; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Host cytoplasm; Reference proteome.
FT   CHAIN           1..312
FT                   /note="Non-structural protein 12A"
FT                   /id="PRO_0000222803"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          63..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          114..162
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..23
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        73..97
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        121..155
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   312 AA;  34175 MW;  720788A5AA39B63D CRC64;
     MFKSGSGSLK RSGSISSVKS FSGDSEKGLP PISRGSVSIT SQNYEPLIVP ANSSSFAAAS
     DFVPEKTKSE GNLKNKSSVI TGNFESSGPT NAHYNQNADG DRLVENLLLK EIAKGRGPST
     SDARHTATDS RLSQEVKQPF SEENAGGNDL NTGRGSHGTG DGIEQYHKSD CEERMSAYHK
     RVVDTFFKYF EYSAEDGHST LYSDVAFLFG CGDLDLLVMS RYQEVMTLRA RSAIYGIFCY
     LQALTAYLTY LGAKVGQVIM LDEELEKYEI RLDVAQDDDP IVFQITTGVF TSGVAHDLRK
     LTQILEAFSL ER