14311_ARATH
ID 14311_ARATH Reviewed; 252 AA.
AC Q9S9Z8; A0JQ87; F4HWN0; Q0WL19;
DT 05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT 16-NOV-2011, sequence version 2.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=14-3-3-like protein GF14 omicron;
DE AltName: Full=General regulatory factor 11;
GN Name=GRF11; OrderedLocusNames=At1g34760; ORFNames=F21H2.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
RC TISSUE=Leaf;
RA Alsterfjord M., Rosenquist M., Larsson C., Sommarin M.;
RT "Novel 14-3-3 isoforms in Arabidopsis thaliana.";
RL Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF Clones.";
RL Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Is associated with a DNA binding complex that binds to the G
CC box, a well-characterized cis-acting DNA regulatory element found in
CC plant genes. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P48349}. Cytoplasm
CC {ECO:0000250|UniProtKB:P48349}. Note=Translocates from the cytosol to
CC the nucleus when phosphorylated. {ECO:0000250|UniProtKB:P48349}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9S9Z8-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9S9Z8-2; Sequence=VSP_042043, VSP_042044;
CC Name=3;
CC IsoId=Q9S9Z8-3; Sequence=VSP_042045;
CC -!- SIMILARITY: Belongs to the 14-3-3 family. {ECO:0000305}.
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DR EMBL; AF323920; AAG47840.1; -; mRNA.
DR EMBL; AC007894; AAD46005.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31735.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31736.1; -; Genomic_DNA.
DR EMBL; AK230390; BAF02188.1; -; mRNA.
DR EMBL; BT029457; ABK59686.1; -; mRNA.
DR RefSeq; NP_001077649.1; NM_001084180.2. [Q9S9Z8-1]
DR RefSeq; NP_564451.2; NM_103196.4. [Q9S9Z8-3]
DR AlphaFoldDB; Q9S9Z8; -.
DR SMR; Q9S9Z8; -.
DR BioGRID; 25612; 10.
DR IntAct; Q9S9Z8; 2.
DR STRING; 3702.AT1G34760.1; -.
DR iPTMnet; Q9S9Z8; -.
DR PaxDb; Q9S9Z8; -.
DR PRIDE; Q9S9Z8; -.
DR ProteomicsDB; 244570; -. [Q9S9Z8-1]
DR EnsemblPlants; AT1G34760.1; AT1G34760.1; AT1G34760. [Q9S9Z8-3]
DR EnsemblPlants; AT1G34760.2; AT1G34760.2; AT1G34760. [Q9S9Z8-1]
DR GeneID; 840380; -.
DR Gramene; AT1G34760.1; AT1G34760.1; AT1G34760. [Q9S9Z8-3]
DR Gramene; AT1G34760.2; AT1G34760.2; AT1G34760. [Q9S9Z8-1]
DR KEGG; ath:AT1G34760; -.
DR Araport; AT1G34760; -.
DR TAIR; locus:2008381; AT1G34760.
DR eggNOG; KOG0841; Eukaryota.
DR HOGENOM; CLU_058290_0_0_1; -.
DR InParanoid; Q9S9Z8; -.
DR OMA; RGHEENA; -.
DR OrthoDB; 1176818at2759; -.
DR PRO; PR:Q9S9Z8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9S9Z8; baseline and differential.
DR Genevisible; Q9S9Z8; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0051117; F:ATPase binding; IDA:TAIR.
DR GO; GO:0008104; P:protein localization; IBA:GO_Central.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR Gene3D; 1.20.190.20; -; 1.
DR InterPro; IPR000308; 14-3-3.
DR InterPro; IPR023409; 14-3-3_CS.
DR InterPro; IPR036815; 14-3-3_dom_sf.
DR InterPro; IPR023410; 14-3-3_domain.
DR PANTHER; PTHR18860; PTHR18860; 1.
DR Pfam; PF00244; 14-3-3; 1.
DR PIRSF; PIRSF000868; 14-3-3; 1.
DR PRINTS; PR00305; 1433ZETA.
DR SMART; SM00101; 14_3_3; 1.
DR SUPFAM; SSF48445; SSF48445; 1.
DR PROSITE; PS00796; 1433_1; 1.
DR PROSITE; PS00797; 1433_2; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Cytoplasm; Nucleus; Phosphoprotein;
KW Reference proteome.
FT CHAIN 1..252
FT /note="14-3-3-like protein GF14 omicron"
FT /id="PRO_0000058673"
FT MOD_RES 65
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P48349"
FT MOD_RES 188
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P48349"
FT VAR_SEQ 241
FT /note="E -> K (in isoform 2)"
FT /evidence="ECO:0000303|Ref.1"
FT /id="VSP_042043"
FT VAR_SEQ 242..252
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.1"
FT /id="VSP_042044"
FT VAR_SEQ 252
FT /note="N -> VNKI (in isoform 3)"
FT /evidence="ECO:0000303|Ref.5"
FT /id="VSP_042045"
FT CONFLICT 128
FT /note="D -> G (in Ref. 4; BAF02188)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 252 AA; 28781 MW; 852335FF39915461 CRC64;
MENERAKQVY LAKLNEQAER YDEMVEAMKK VAALDVELTI EERNLLSVGY KNVIGARRAS
WRILSSIEQK EESKGNEQNA KRIKDYRTKV EEELSKICYD ILAVIDKHLV PFATSGESTV
FYYKMKGDYF RYLAEFKSGA DREEAADLSL KAYEAATSSA STELSTTHPI RLGLALNFSV
FYYEILNSPE RACHLAKRAF DEAIAELDSL NEDSYKDSTL IMQLLRDNLT LWTSDLEEGG
EQSKGHNQQD EN