ID   NSP6_ROTBU              Reviewed;          98 AA.
AC   P0C6Z2;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-APR-2009, sequence version 1.
DT   03-AUG-2022, entry version 27.
DE   RecName: Full=Non-structural protein 6 {ECO:0000255|HAMAP-Rule:MF_04093};
DE            Short=NSP6 {ECO:0000255|HAMAP-Rule:MF_04093};
OS   Rotavirus A (strain RVA/Cow/United Kingdom/UK/1975/G6P7[5]) (RV-A).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Rotavirus; Rotavirus A.
OX   NCBI_TaxID=10934;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2998051; DOI=10.1016/0042-6822(85)90275-2;
RA   Ward C.W., Azad A.A., Dyall-Smith M.L.;
RT   "Structural homologies between RNA gene segments 10 and 11 from UK bovine,
RT   simian SA11, and human Wa rotaviruses.";
RL   Virology 144:328-336(1985).
RN   [2]
RP   CHARACTERIZATION, AND SUBCELLULAR LOCATION.
RX   PubMed=17658646; DOI=10.1016/j.virusres.2007.06.011;
RA   Rainsford E.W., McCrae M.A.;
RT   "Characterization of the NSP6 protein product of rotavirus gene 11.";
RL   Virus Res. 130:193-201(2007).
CC   -!- SUBUNIT: Interacts with NSP2 and NSP5. {ECO:0000255|HAMAP-
CC       Rule:MF_04093}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04093,
CC       ECO:0000269|PubMed:17658646}. Host mitochondrion {ECO:0000255|HAMAP-
CC       Rule:MF_04093}. Note=Found in spherical cytoplasmic structures, called
CC       viral factories, that appear early after infection and are the site of
CC       viral replication and packaging. {ECO:0000255|HAMAP-Rule:MF_04093}.
CC   -!- SIMILARITY: Belongs to the rotavirus A NSP6 family. {ECO:0000255|HAMAP-
CC       Rule:MF_04093}.
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DR   EMBL; K03385; -; NOT_ANNOTATED_CDS; Genomic_RNA.
DR   SMR; P0C6Z2; -.
DR   Proteomes; UP000008657; Genome.
DR   GO; GO:0033650; C:host cell mitochondrion; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_04093; ROTA_NSP6; 1.
DR   InterPro; IPR006950; Rotavirus_NSP6.
DR   Pfam; PF04866; Rota_NS6; 1.
PE   1: Evidence at protein level;
KW   Host cytoplasm; Host mitochondrion.
FT   CHAIN           1..98
FT                   /note="Non-structural protein 6"
FT                   /id="PRO_0000369514"
SQ   SEQUENCE   98 AA;  11693 MW;  C9752DA122E325E5 CRC64;
     MNHLQQRQLF LENLLVGVNN MFHQMQKRPV NTCCRSLQKI LDHLILLQTI HSPAFRLDQM
     QLRQMQTLAC LWIHQYNHDH QVTLGAIKWI SPLIKELK