ID   NSP6_ROTHD              Reviewed;          92 AA.
AC   B3SRT4;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   02-DEC-2020, entry version 34.
DE   RecName: Full=Non-structural protein 6 {ECO:0000255|HAMAP-Rule:MF_04093};
DE            Short=NSP6 {ECO:0000255|HAMAP-Rule:MF_04093};
OS   Rotavirus A (strain RVA/Human/United States/DS-1/1976/G2P1B[4]) (RV-A)
OS   (Rotavirus A (strain DS1)).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Rotavirus; Rotavirus A.
OX   NCBI_TaxID=10950;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2152809; DOI=10.1128/jvi.64.1.120-124.1990;
RA   Matsui S.M., Mackow E.R., Matsuno S., Paul P.S., Greenberg H.B.;
RT   "Sequence analysis of gene 11 equivalents from 'short' and 'super short'
RT   strains of rotavirus.";
RL   J. Virol. 64:120-124(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=18786998; DOI=10.1128/jvi.01402-08;
RA   Heiman E.M., McDonald S.M., Barro M., Taraporewala Z.F., Bar-Magen T.,
RA   Patton J.T.;
RT   "Group A human rotavirus genomics: evidence that gene constellations are
RT   influenced by viral protein interactions.";
RL   J. Virol. 82:11106-11116(2008).
CC   -!- SUBUNIT: Interacts with NSP2 and NSP5. {ECO:0000255|HAMAP-
CC       Rule:MF_04093}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04093}.
CC       Host mitochondrion {ECO:0000255|HAMAP-Rule:MF_04093}. Note=Found in
CC       spherical cytoplasmic structures, called viral factories, that appear
CC       early after infection and are the site of viral replication and
CC       packaging. {ECO:0000255|HAMAP-Rule:MF_04093}.
CC   -!- SIMILARITY: Belongs to the rotavirus A NSP6 family. {ECO:0000255|HAMAP-
CC       Rule:MF_04093}.
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DR   EMBL; M33608; AAA47327.1; -; Genomic_RNA.
DR   EMBL; EF672583; ABV53259.1; -; Genomic_RNA.
DR   Proteomes; UP000001457; Genome.
DR   GO; GO:0033650; C:host cell mitochondrion; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_04093; ROTA_NSP6; 1.
DR   InterPro; IPR006950; Rotavirus_NSP6.
DR   Pfam; PF04866; Rota_NS6; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Host mitochondrion.
FT   CHAIN           1..92
FT                   /note="Non-structural protein 6"
FT                   /id="PRO_0000369523"
FT   CONFLICT        30
FT                   /note="I -> E (in Ref. 1)"
SQ   SEQUENCE   92 AA;  11014 MW;  33748C9C39421F9E CRC64;
     MNRLQQRQLF LENLLVGVNS TFHQMQKLSI NTCCQNLQKI LDLLILHRTI HSPAFRLDRM
     QLRQMQMLAC LWIHQRNHDH LATLDTIKWI SP