ID   NSRR_OCEIH              Reviewed;         147 AA.
AC   Q8ETG9;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=HTH-type transcriptional regulator NsrR;
GN   Name=nsrR; OrderedLocusNames=OB0292;
OS   Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC
OS   3954 / HTE831).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Oceanobacillus.
OX   NCBI_TaxID=221109;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831;
RX   PubMed=12235376; DOI=10.1093/nar/gkf526;
RA   Takami H., Takaki Y., Uchiyama I.;
RT   "Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge
RT   and its unexpected adaptive capabilities to extreme environments.";
RL   Nucleic Acids Res. 30:3927-3935(2002).
CC   -!- FUNCTION: Nitric oxide-responsive transcriptional regulator.
CC       {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135; Evidence={ECO:0000305};
CC       Note=Binds 1 [2Fe-2S] cluster per subunit. {ECO:0000305};
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DR   EMBL; BA000028; BAC12248.1; -; Genomic_DNA.
DR   RefSeq; WP_011064694.1; NC_004193.1.
DR   AlphaFoldDB; Q8ETG9; -.
DR   SMR; Q8ETG9; -.
DR   STRING; 221109.22775971; -.
DR   EnsemblBacteria; BAC12248; BAC12248; BAC12248.
DR   KEGG; oih:OB0292; -.
DR   eggNOG; COG1959; Bacteria.
DR   HOGENOM; CLU_107144_2_1_9; -.
DR   OMA; AQEAFYA; -.
DR   OrthoDB; 1765806at2; -.
DR   PhylomeDB; Q8ETG9; -.
DR   Proteomes; UP000000822; Chromosome.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000944; Tscrpt_reg_Rrf2.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR33221; PTHR33221; 1.
DR   Pfam; PF02082; Rrf2; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   TIGRFAMs; TIGR00738; rrf2_super; 1.
DR   PROSITE; PS51197; HTH_RRF2_2; 1.
PE   3: Inferred from homology;
KW   2Fe-2S; DNA-binding; Iron; Iron-sulfur; Metal-binding; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..147
FT                   /note="HTH-type transcriptional regulator NsrR"
FT                   /id="PRO_0000271135"
FT   DOMAIN          2..133
FT                   /note="HTH rrf2-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00540"
FT   DNA_BIND        28..51
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00540"
FT   BINDING         92
FT                   /ligand="[2Fe-2S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:190135"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00540"
FT   BINDING         100
FT                   /ligand="[2Fe-2S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:190135"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00540"
FT   BINDING         106
FT                   /ligand="[2Fe-2S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:190135"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00540"
SQ   SEQUENCE   147 AA;  16726 MW;  3A2BC10F8C6899F7 CRC64;
     MNLKKYTDYA LRVLIFTGLK SDQELANIKE IAEVYQISQE HLRKVVHELT KMELVVTIRG
     RNGGIKLAKP ASEINIGLLI RQLENDFVLL ECFDKGTNHC VISPGCTLKH VINKALVAFF
     KVLEEYTLED LIKNEEELLA LMGIEKV